Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...

    STTR Phase I 2008 Department of Health and Human Services
  2. A device containing immobilized chelator to remove aluminum from TPN solutions

    SBC: ALKYMOS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A high percentage of the ~ 470,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common conta ...

    STTR Phase I 2008 Department of Health and Human Services
  3. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A Large Size 3D Holographic Display with PR Polymers

    SBC: BOSTON APPLIED TECHNOLOGIES, INCORPORATED            Topic: AF08T001

    In this STTR project, Boston Applied Technologies, Inc. (BATi), teaming up with Prof. Di Bartolo’s group at Boston College, aims at developing a large size (300 mm x 300 mm) updatable 3D display with photorefractive polymers for battlefield and command and control applications. The proposed 3D display system features fast response (feasible to video-rate), high diffraction efficiency, and relati ...

    STTR Phase I 2008 Department of DefenseAir Force
  5. A low-cost point-of-care diagnostic test for simultaneous HIV-1 and STI

    SBC: Infoscitex Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): An important approach for HIV/AIDS prevention is to diagnose co-infections that significantly increase the transmission of HIV. In this proposal, we propose to develop a rapid point-of-care (POC) test that simultaneous ly diagnoses HIV-1 and two sexually transmitted infections (STI's). Syphilis and genital herpes are STI's that enhance HIV transmission; if dia ...

    STTR Phase I 2008 Department of Health and Human Services
  6. A smart needle guide template for MRI-guided transperineal prostate biopsy

    SBC: Physical Sciences Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

    STTR Phase I 2014 Department of Health and Human Services
  7. Adaptive Hierarchical Multiple Models to Control Dynamic Systems

    SBC: Scientific Systems Company Inc.            Topic: AF07T012

    Modern control theory offers mathematically rigorous and powerful solutions to many dynamic systems. Its limitations are that the classes of dynamic systems covered by the theory are limited to linear systems or certain well-structured nonlinear systems, and the adaptation of the controllers are often slow if the controller parameters are far away from their desired values. On the other hand, the ...

    STTR Phase I 2008 Department of DefenseAir Force
  8. Advanced Technology and Tools for DBS Programming for Speech Functionality

    SBC: SPEECH TECHNOLOGY/APPLIED RESEARCH CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Speech is a complex motor behavior often disrupted by neurological dysfunction. Parkinson's disease (PD) is one of the main disorders disrupting speech. Recently, deep brain stimulation (DBS) has proven to be effective for motor problems in patients with PD and other movement disorders. However, the effects of DBS on speech have not been consistently positive ...

    STTR Phase II 2008 Department of Health and Human Services
  9. Advanced Window Materials for High Energy Propulsion

    SBC: CERANOVA CORPORATION            Topic: AF07T009

    Window materials are an essential component of some advanced propulsion concepts which require high pressures, high temperatures, low energy losses, and low weights. Window materials must possess a combination of properties such as high mechanical strength, high melting point, high transparency, low density, and good resistance to the operating environment. CeraNova proposes the development of f ...

    STTR Phase I 2008 Department of DefenseAir Force
  10. Alkoxylamine nucleosides for sequencing by synthesis

    SBC: INTELLIGENT BIO-SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Sequencing during synthesis (SdS) is an architecture for massively parallel DNA sequencing that has the strong potential of lowering the cost of sequencing enough to allow individuals access to their own genetic heritag e as a way of personalizing their medical care. Thus far, however, higher-throughput next-generation sequencing systems are relatively expensiv ...

    STTR Phase II 2008 Department of Health and Human Services
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