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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advanced Technology and Tools for DBS Programming for Speech Functionality

    SBC: Speech Technology and Applied Research Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Speech is a complex motor behavior often disrupted by neurological dysfunction. Parkinson's disease (PD) is one of the main disorders disrupting speech. Recently, deep brain stimulation (DBS) has proven to be effective for motor problems in patients with PD and other movement disorders. However, the effects of DBS on speech have not been consistently positive ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A General-Purpose Software Tool for Multi-disciplinary Simulation Data Management and Learning

    SBC: CFD RESEARCH CORPORATION            Topic: AF11BT27

    ABSTRACT: The overall goal of the proposed effort is to develop and demonstrate a general-purpose, fast, and reliable management and learning software tool for analyzing massive data sets generated by dynamic multi-disciplinary simulation. In Phase I, key technology elements were developed and proof-of-principle was successfully demonstrated. Data management software encapsulating salient feature ...

    STTR Phase II 2014 Department of DefenseAir Force
  4. Alkoxylamine nucleosides for sequencing by synthesis

    SBC: INTELLIGENT BIO-SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Sequencing during synthesis (SdS) is an architecture for massively parallel DNA sequencing that has the strong potential of lowering the cost of sequencing enough to allow individuals access to their own genetic heritag e as a way of personalizing their medical care. Thus far, however, higher-throughput next-generation sequencing systems are relatively expensiv ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Cancer dual-targeting of an infectivity-enhance CRAd

    SBC: VECTORLOGICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Studies of the molecular mechanisms underlying neoplastic transformation and progression have resulted in the understanding that cancer is a genetic disease, deriving from the accumulation of a series of acquired genet ic lesions. Despite advances in chemotherapy, radiation delivery, and surgical treatment regimens, survival from many advanced cancers remains ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Commercial Methods for Production of Orientation Patterned GaAs

    SBC: PHYSICAL SCIENCES INC.            Topic: AF06T010

    The Air Force desires development of a commercial production source for nonlinear optical (NLO) gallium arsenide semiconductor crystals with orientation patterning, i.e., OP-GaAs. The Phase I project has demonstrated feasibility for a fabrication method of OP-GaAs which exclusively utilizes processes anticipated to be available from commercial vendors and at Physical Sciences Inc (PSI). Molecula ...

    STTR Phase II 2008 Department of DefenseAir Force
  9. Computational Model for Electrode Erosion by High-Pressure Moving Arcs

    SBC: CFD RESEARCH CORPORATION            Topic: AF11BT25

    ABSTRACT: The goal of this project is to develop theoretical models for electrode erosion in high-pressure arcs and incorporate them into computational tools for simulations of arc heaters. The complexity of the electrode material removal process is associated with the multi-phase nature of the arc-electrode interactions, melting and vaporization of the electrodes near the arc foot. Available mod ...

    STTR Phase II 2014 Department of DefenseAir Force
  10. Developmental Disabilites Early Intervention Training

    SBC: PRAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Federal and state laws require that young children with disabilities or who are at risk for developing disabilities be provided with Early Intervention services according to their developmental needs. But currently ther e is a critical shortage of skilled EI providers. The primary reason for this shortage is a lack of educational and training programs. Except f ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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