Award Data

DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...

In this effort, Innoveering will integrate and test a closed-loop active control system for scramjet isolator shock system positioning. The approach is to control the fuel flow to the engine to position the shock train leading edge at a specified location in the isolator. The control system includes three basic elements: a shock position sensing system based, a fast response fuel valve that adjust ...

ABSTRACT: In this effort selected SBIR technologies will be matured and merged to establish the Adaptive Cyber-secure Cross-layer Communications-Classification System (AC4S) for enhancing the throughput, spectral efficiency, speed, reliability and security performance of software defined radio (SDR) communication networks. One of the core technologies in the AC4S architecture is the Cyber Superior ...

ABSTRACT: In this effort selected SBIR technologies will be matured and merged to establish the Adaptive Cyber-secure Cross-layer Communications-Classification System (AC4S) for enhancing the throughput, spectral efficiency, speed, reliability and security performance of software defined radio (SDR) communication networks. One of the core technologies that forms the basis of AC4S is the AXL-ROSA s ...

Modern control theory offers mathematically rigorous and powerful solutions to many dynamic systems. Its limitations are that the classes of dynamic systems covered by the theory are limited to linear systems or certain well-structured nonlinear systems, and the adaptation of the controllers are often slow if the controller parameters are far away from their desired values. On the other hand, the ...

DESCRIPTION (provided by applicant): A high percentage of the ~ 470,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common conta ...

DESCRIPTION (provided by applicant): Speech is a complex motor behavior often disrupted by neurological dysfunction. Parkinson's disease (PD) is one of the main disorders disrupting speech. Recently, deep brain stimulation (DBS) has proven to be effective for motor problems in patients with PD and other movement disorders. However, the effects of DBS on speech have not been consistently positive ...

Window materials are an essential component of some advanced propulsion concepts which require high pressures, high temperatures, low energy losses, and low weights. Window materials must possess a combination of properties such as high mechanical strength, high melting point, high transparency, low density, and good resistance to the operating environment. CeraNova proposes the development of f ...

DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

DESCRIPTION (provided by applicant): Solidus Biosciences, Inc. in partnership with the University of California, Berkeley, and Rensselaer Polytechnic Institute are proposing to address a critical need in drug safety technology through its proprietary meta bolic stability chip (or Metabolizing Enzyme Stability Assay Chip, or MesaChip) for high-throughput analysis of drug candidate metabolism. The ...