Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Large Size 3D Holographic Display with PR Polymers


    In this STTR project, Boston Applied Technologies, Inc. (BATi), teaming up with Prof. Di Bartolo’s group at Boston College, aims at developing a large size (300 mm x 300 mm) updatable 3D display with photorefractive polymers for battlefield and command and control applications. The proposed 3D display system features fast response (feasible to video-rate), high diffraction efficiency, and relati ...

    STTR Phase I 2008 Department of DefenseAir Force
  3. Adaptive Hierarchical Multiple Models to Control Dynamic Systems

    SBC: Scientific Systems Company Inc.            Topic: AF07T012

    Modern control theory offers mathematically rigorous and powerful solutions to many dynamic systems. Its limitations are that the classes of dynamic systems covered by the theory are limited to linear systems or certain well-structured nonlinear systems, and the adaptation of the controllers are often slow if the controller parameters are far away from their desired values. On the other hand, the ...

    STTR Phase I 2008 Department of DefenseAir Force
  4. Advanced Window Materials for High Energy Propulsion

    SBC: CERANOVA CORPORATION            Topic: AF07T009

    Window materials are an essential component of some advanced propulsion concepts which require high pressures, high temperatures, low energy losses, and low weights. Window materials must possess a combination of properties such as high mechanical strength, high melting point, high transparency, low density, and good resistance to the operating environment. CeraNova proposes the development of f ...

    STTR Phase I 2008 Department of DefenseAir Force
  5. An Equilibrated Micromachined Pressure (EMP) Sensor for Hypersonic Transients


    Research Support Instruments, Inc. (RSI), with the aid of Princeton University, proposes to develop an Equilibrated Micromachined Pressure (EMP) sensor for measuring hypersonic transients with amplitudes < 1 Torr and frequencies of hundreds of kHz.Existing micromachined transducers include capacitive, resistive, or optical techniques. Transducers using silicon membranes and piezoresistive or capa ...

    STTR Phase I 2003 Department of DefenseAir Force
  6. Application of Cortical Processing Theory to Acoustical Analysis

    SBC: Sensimetrics Corporation            Topic: N/A

    This research proposal aims at formulating signal processing principles realized by the auditory system, in particular when the input signal is speech. Two specific aims are: (1) to model the role of the descending pathway in stabilizing AN representationsof speech sounds in degraded acoustic conditions. Current models of the auditory periphery are based upon the ascending pathway up through the A ...

    STTR Phase I 2003 Department of DefenseAir Force
  7. Automated Diagnosis of Usability Problems Using Statistical Computational Methods

    SBC: Aptima, Inc.            Topic: N/A

    The effects of poor usability range from mere inconvenience to disaster. Human factors specialists employ usability analysis to reduce the likelihood or impact of such failures. However, good usability analysis requires usability reports that are rarelycollected, rarely complete, and difficult to analyze.Aptima and the Center for Intelligent Information Retrieval (U. Mass. Amherst) have partnered ...

    STTR Phase I 2003 Department of DefenseAir Force
  8. Biomimetic Microstructure Formation of High Performance Silk Films and Fibers

    SBC: FOSTER-MILLER, INC.            Topic: N/A

    The complex biological processing used by the silkworm and spider to create silk fibers yields exceptionally high strength, stiffness, and extensibility. In this proposed program, Foster-Miller will again join with Prof. David Kaplan and theBiotechnology Center at Tufts University to develop fibers and films based on reconstituted silkworm silk that possess unique and tailorable properties for e ...

    STTR Phase II 2003 Department of DefenseAir Force
  9. Brain penetrant Hsp90 inhibitors for Alzheimer's disease


    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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