Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Framework for Modeling and Analyzing Complex Distributed Systems

    SBC: VEROMODO, INC.            Topic: AF04T023

    Summary and intellectual merit. This Small Business Technology Transfer Phase I project will develop a modeling language and computational support tools for specifying, analyzing, and verifying complex distributed system designs. The overall modeling and analysis framework will provide an integrated suite of tools and methods ultimately leading to qualitative improvements in the design ...

    STTR Phase I 2004 Department of DefenseAir Force
  3. A Large Size 3D Holographic Display with PR Polymers

    SBC: BOSTON APPLIED TECHNOLOGIES, INCORPORATED            Topic: AF08T001

    In this STTR project, Boston Applied Technologies, Inc. (BATi), teaming up with Prof. Di Bartolo’s group at Boston College, aims at developing a large size (300 mm x 300 mm) updatable 3D display with photorefractive polymers for battlefield and command and control applications. The proposed 3D display system features fast response (feasible to video-rate), high diffraction efficiency, and relati ...

    STTR Phase I 2008 Department of DefenseAir Force
  4. Active Silicon Nanophotonics based on Photonic Crystal with Quantum Dots

    SBC: Altair Center, Llc.            Topic: AF04T013

    ALTAIR Center in cooperation with University of Rochester proposes to develop a new class of active nanophotonic devices based on quantum dots embedded into photonic crystal microstructures fabricated in silicon-on-insulator waveguides. Due to extremely strong nonlinear optical and electro-optical properties and extremely short switching times, the silicon-based photonic crystal microstructures wi ...

    STTR Phase I 2004 Department of DefenseAir Force
  5. Adaptive Hierarchical Multiple Models to Control Dynamic Systems

    SBC: Scientific Systems Company Inc.            Topic: AF07T012

    Modern control theory offers mathematically rigorous and powerful solutions to many dynamic systems. Its limitations are that the classes of dynamic systems covered by the theory are limited to linear systems or certain well-structured nonlinear systems, and the adaptation of the controllers are often slow if the controller parameters are far away from their desired values. On the other hand, the ...

    STTR Phase I 2008 Department of DefenseAir Force
  6. Advanced Composites with Nanoscale Reinforcement

    SBC: Nanolab, Inc            Topic: AF04T020

    Advanced fiber composites are fabricated by automated 3D weaving and braiding processes. These weaving processes use tows of micron diameter fibers, to create preforms for resin infiltration. The interaction between the resin matrix and the fibers can be potentially increased by creating nanoscale features on the carbon fibers. NanoLab is expert in the synthesis of carbon nanotubes and their app ...

    STTR Phase I 2004 Department of DefenseAir Force
  7. Advanced Window Materials for High Energy Propulsion

    SBC: CERANOVA CORPORATION            Topic: AF07T009

    Window materials are an essential component of some advanced propulsion concepts which require high pressures, high temperatures, low energy losses, and low weights. Window materials must possess a combination of properties such as high mechanical strength, high melting point, high transparency, low density, and good resistance to the operating environment. CeraNova proposes the development of f ...

    STTR Phase I 2008 Department of DefenseAir Force
  8. Automated Diagnosis of Usability Problems Using Statistical Computational Methods

    SBC: Aptima, Inc.            Topic: AF03T001

    Poorly designed software and hardware systems are inconvenient at best; at worst, they are deadly. Usability evaluation techniques are designed to detect the potential for disasters and inefficiencies in poorly designed software. However, usability analyses are prone to failure due to conflicting usability frameworks, incomplete usability reports, and inadequate analysis tools. Aptima and the Ce ...

    STTR Phase II 2004 Department of DefenseAir Force
  9. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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