Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A universal mechanobiology tool for drug discovery in lung diseases

    SBC: Mechanobiologix L.L.C.            Topic: NHLBI

    Abstract Despite significant effortsno cure exists for the major respiratory diseases such as asthmaemphysema and pulmonary fibrosis due to a lack of proper preclinical methodsDrug development is often carried out in cultured cellsWhile amenable to imaging and manipulationthis approach lacks the native tissue environment and neglects the effects of mechanical forces due to breathing which influenc ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Mobile Tai Chi Platform for Fall Prevention in Older Adults

    SBC: BioSensics LLC            Topic: NIA

    Project Summary The overall goal of the proposed work is to develop a platform capable of delivering and monitoring adherenceproficiencyand safety of a home based simplified Tai Chi intervention for older adultsDuring Phase I of this Fast Track STTR project we will further develop a novel approach to assessing Tai Chi performance adherenceproficiencyand safety based on wearable sensor dataMetrics ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid High-Fidelity Assembly of Challenging Peptide Sequences

    SBC: Velum Incorporated            Topic: NIGMS

    PROJECT SUMMARY Peptide therapeutics combine high potency and selectivity with fewer side effects than traditional small moleculesThis has fueled interest in peptides filling the gap betweenbiologicsand small molecules as compounds that have the key desired properties from both the other classesWorldwide peptide drug sales surpassed $billion inof which nearly $billion was in the USAwith projected ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Discovery of TrkC agonist antibodies for hearing loss

    SBC: Zebra Biologics, Inc.            Topic: NIDCD

    ! Project Summary AbstractSensori neural hearing lossSNHLis caused by several factorsincluding excessive noisedrug toxin exposure and genetic lesionsTaken togetherhearing deficits represent the number one neurological disorder worldwideDespite numerous past and ongoing clinical studies there is currently no effective therapeutic treatment for hearing loss and its associated decline in quality of l ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functionsmemoryattentionlanguag ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living

    SBC: BioSensics LLC            Topic: NIA

    With a Phase I II STTR grant award from NIABioSensics in collaboration with Baylor College of MedicineBCMsuccessfully developed and commercialized an advanced physical activity monitoring systemPAMSysfor older adultsPAMSys enables continuous remote monitoring of physical activityfall riskand fall incidentsThe fall detection technology of PAMSys has become the gold standard in the medical alert ind ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Southeast Xlerator Network

    SBC: XLERATEHEALTH, LLC            Topic: R

    The Southeast XLerator Network proposes to create a networked and easily accessible regional technology transfer accelerator hub XLerator Hub or Hub to share best practices disseminate education content and offer products services facilities and other resources connected through both physical and online platforms for innovators and trainees in the Southeast IDeA states Led by XLerateHealth LLC an ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Drug-eluting Brachytherapy Implants for Chemo-radiation Therapy

    SBC: TheraNano LLC            Topic: 102

    Theranano LLC in collaboration with internationally renowned prostate brachytherapy clinicians at Brigham and Womens Hospital and Dana Farber Cancer Institute and biomaterials experts at Northeastern University have developed an innovative combinatorial treatment strategy of Local ChemoRadiation TherapyLCRTusing a modified brachytherapy spacer platform in the form of a INCeRTImplaNts for ChemoRadi ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Improving ALS Diagnosis using Needle I-EMG

    SBC: HAYSTACK DIAGNOSTICS, INC.            Topic: 103

    PROJECT SUMMARY Needle electromyographyEMGremains the standard approach for assessing neuromuscular diseaseWhile the technique has proven to be clinically valuable over the lastyearsit has important limitationsThese include its not being sensitive to alterations in muscle composition and structureits inability to assess the contractile apparatus of muscleand its subjective nature with an inter rat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development and evaluation of diffuse correlation spectroscopy to monitor cerebral blood flow and detect intraventricular hemorrhage in extremely premature infants

    SBC: 149 Medical Inc.            Topic: 103

    PROJECT SUMMARY ABSTRACT Every year in the United States aboutof theinfants born extremely prematureandltweeks gestational age and andltg birth weightELGAdevelop intraventricular hemorrhageIVHIVH is associated with high risk for cerebral palsy and significant intellectual disabilitycausing lifelong implications for affected children and their families and considerable economic burdenIVH is caused ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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