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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Airborne Video Inspection for Automatic Targeting with Ontology Reasoning (AVIATOR)

    SBC: Charles River Analytics, Inc.            Topic: AF18BT007

    Improved cameras and unmanned air vehicles (UAVs) have led to an explosion in the amount of airborne imagery and video collected by Air Force assets, but there are not enough trained personnel to analyze this imagery in real time. Thus, targets of opportunity and threats go undetected until the chance to act on them has passed. Automatic target detection could alleviate the burden on analysts and ...

    STTR Phase I 2019 Department of DefenseAir Force
  3. A Mobile Tai Chi Platform for Fall Prevention in Older Adults

    SBC: BioSensics LLC            Topic: NIA

    Project Summary The overall goal of the proposed work is to develop a platform capable of delivering and monitoring adherence, proficiency, and safety of a home-based simplified Tai Chi intervention for older adults. During Phase I of this Fast-Track STTR project we will further develop a novel approach to assessing Tai Chi performance adherence, proficiency, and safety based on wearable sensor da ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living

    SBC: BioSensics LLC            Topic: NIA

    With a Phase I/II STTR grant award from NIA, BioSensics in collaboration with Baylor College of Medicine (BCM) successfully developed and commercialized an advanced physical activity monitoring system (PAMSys™) for older adults. PAMSys enables continuous remote monitoring of physical activity, fall risk, and fall incidents. The fall detection technology of PAMSys has become the gold standard in ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A smart needle guide template for MRI-guided transperineal prostate biopsy

    SBC: Physical Sciences Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A universal mechanobiology tool for drug discovery in lung diseases

    SBC: Mechanobiologix L.L.C.            Topic: NHLBI

    Abstract Despite significant effortsno cure exists for the major respiratory diseases such as asthmaemphysema and pulmonary fibrosis due to a lack of proper preclinical methodsDrug development is often carried out in cultured cellsWhile amenable to imaging and manipulationthis approach lacks the native tissue environment and neglects the effects of mechanical forces due to breathing which influenc ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. AutoRegister: A system for enhancing the accuracy of tumor change detection

    SBC: CORTICOMETRICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. BATTLE II: Battlefield Airmen Training Technologies for LVC, ground-based Environments

    SBC: Aptima, Inc.            Topic: AF17AT011

    Effective Live, Virtual, and Constructive (LVC) training methods have been underutilized within ground-based training operations. More specifically, Battlefield Airmen training has not adopted the recent advances in blended reality (BR) technologies into their training due to specialized training requirements. To address this issue, the Aptima team plans to continue develop on a training system kn ...

    STTR Phase II 2019 Department of DefenseAir Force
  9. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Carbon Nanotube FET Modeling and RF circuits

    SBC: Metis Design Corporation            Topic: AF18BT006

    The computing demands of future data-intensive applications far exceed the capabilities of today’s electronics and cannot be met by isolated improvements in transistor technologies or integrated circuit (IC) architectures alone. Carbon Nanotube Field-Effect Transistors (CNFET) technology has emerged as leading candidate for energy-efficient and high-performance digital systems. Unfortunatel ...

    STTR Phase I 2019 Department of DefenseAir Force
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