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DESCRIPTION provided by applicant Diffuse large B cell lymphoma DLBCL represents one of the most common variants of Non Hodgkinandapos s lymphoma NHL and oncogenic herpesviruses EBV and KSHV are the etiologic agents for the majority of these tumors in patients over or those infected with the human immunodeficiency virus HIV Despite modest improvements in outcomes for patients rece ...

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

DESCRIPTION provided by applicant Lipella Pharmaceuticals Inc Pittsburgh PA is a clinical stage pharmaceutical company specializing in intravesical therapies for urinary bladder dysfunctions Lipella is submitting a research proposal to the Small Business Technology Transfer program titled andquot Developing Intravesical Liposomes for Interstitial Cystitisandquot The project proposes to e ...

DESCRIPTION provided by applicant Widespread antibiotic use has accelerated S aureus resistance to almost all marketed antibiotic classes including beta lactams fluoroquinolones macrolides aminoglycosides tetracyclines as well as the newer linezolid and daptomycin Methicillin resistant S aureus MRSA is an increasing public health threat with deaths from MRSA infections already compar ...

DESCRIPTION provided by applicant This is a collaborative proposal to develop inhibitors with reduced susceptibility to resistance and improved genotype spectrum of activity against the NS A protease of the Hepatitis C virus HCV Over three percent of the worldandapos s population is infected with the hepatitis C virus HCV Unfortunately the current best treatment is still quite challeng ...

ABSTRACT: The objective of this project is to move an energy efficient process for the conversion of carbon dioxide and water into syngas, a key feedstock for the production of synthetic chemicals. BENEFIT: If we are successful we will have a new process to convert air water and sunlight into transportation fuels. That will result in a domestic source of fuels that does not compete with the foo ...

This project address the fabrication of solar blind detectors from the MgZnO material system. Both MBE and MOCVD material growth techniques will be used for deposition of the required material layers. Simulation software we be used to aid in the design of the photodetector structure. Devices will be fabricated from the grown structures and their electrical and optical characteristics determined.

Two-electron reduced-density-matrix (2-RDM) methods represent all of the electrons in any molecule or material with only two electrons by replacing the wave function by the 2-RDM as the basic variable for quantum many-electron theory. The 2-RDM methods, developed by David Mazziotti at The University of Chicago with support from the Army Research Office, have polynomial scaling with system size, al ...

We propose a rapid mapping and 3-D visualization system especially suited for inside buildings, tunnels, urban canyons, and other environments where GPS may be poor or not available. The system--which was fully demonstrated in our Phase I effort-- includes mobile Sensor Nodes that wirelessly supply compressed 3D range data and color imagery to a central Fusion Node. The Fusion Node runs 3D recon ...

ABSTRACT: CU Aerospace (CUA) and team partner the University of Illinois at Urbana-Champaign (UIUC) propose to perform research, development and demonstration of experimental quenching free measurements of heat-release in a realistic highly turbulent plasma-assisted flame. Kinetics models will be correspondingly updated and detailed 3D multiphysics simulations will be validated by the measuremen ...