Award Data

DESCRIPTION (provided by applicant): People living with HIV or AIDS (PLWHA) are often prescribed an antiretroviral regimen to decrease risk for opportunistic infection. These multi-medication regimens are highly complex and burdensome and require almost perfect adherence. Consequently, poor antiretroviral adherence is a vexing problem. We propose an engaging, literacy- and motivationally tailored ...

Advance millimeter wave (MMW) transceivers are needed to further enhance the U.S. military current and future communication, detection and guidance systems. TLC will develop and demonstrate a unique low-cost, wire-bond-free, 70-94 GHz W-band antennaintegrated MMIC transceiver that also meet commercial performance, low price, and simplicity requirements. This transceiver will also provide excelle ...

DESCRIPTION (provided by applicant): The CF Quantum(r) sweat test system is a rapid, easily administered, cost effective method to diagnose cystic fibrosis (CF). The CF Quantum(r) patch (Q-patch) uses an ion-exchange reaction to produce a white precipitate which varies in size based on the chloride ion concentration of the sweat sample. Reacting the Q-patch with a chloride-containing solution (i.e ...

DESCRIPTION (provided by applicant): The CF Quantum(r) sweat test system is a rapid, easily administered, cost effective method to diagnose cystic fibrosis (CF). The CF Quantum(r) patch (Q-patch) uses an ion-exchange reaction to produce a white precipitate which varies in size based on the chloride ion concentration of the sweat sample. Reacting the Q-patch with a chloride-containing solution (i.e ...

A Publish and Subscribe (P&S) architecture forms the foundation of the Joint Battlespace Infosphere (JBI) system, which is composed of protocols, processes, and common core functions permitting participating applications and organizations to share andexchange mission-critical information in a timely manner. The Air Force is examining various P&S standards that have the potential of forming the bas ...

DESCRIPTION (provided by applicant): Antisense oligonucleotides have generated enormous interest as therapeutic molecules since their initial demonstration in 1978, but their full utilization as effective human therapies has been hampered by inadequate drug delivery to the correct cellular compartment of the correct tissue. We have designed a water-based, ultra-small nanocapsule formulation for ...

DESCRIPTION (provided by applicant): Neurovascular lesions, such as aneurysms and arteriovenous malformations (AVMs), are insidious and unpredictable. They often go unnoticed until the occurrence of a catastrophic hemorrhage or stroke. Approximately 350,000 patients experience hemorrhage annually, resulting in permanent loss of motor function, seizures, and death. Current neurosurgical therapie ...

Current military and commercial communication systems at lower frequencies experience spectrum crowding, and does not have wide bandwidths needed for high data rates. Broadband Low Noise Amplifiers (LNA) are crucial components in any receiver system.Although a wide variety of LNAs are currently available in the frequency bands below 50 GHz, little development has occurred in the 49 to 52 GHz range ...

DESCRIPTION (provided by applicant): The development of an alternative to the currently available synthetic vascular prosthesis is of great value. Atherosclerosis vascular disease, in the form of coronary artery and peripheral vascular disease, is the leading cause of mortality in the United States. Despite vast improvements in the field of biomaterials, a useful biocompatible material is still no ...

DESCRIPTION (provided by applicant): Treatment of ischemia by administration of bone marrow (BM)-derived endothelial progenitor cells (EPC) or ex vivo expanded EPC populations has been shown to enhance vascular regeneration in animal models and in clinical trials. For cell therapy to be practical in a clinical setting, simple, efficient, GMP compliant methods for cell production are needed. Aastro ...