Award Data

DESCRIPTION (provided by applicant): Point of care testing is a test that is performed near or at the site of care. In addition it has come to imply a rapid turnaround time, ease of use and convenience for the patient. Traditional Point of Care single usecartridge tests are lateral flow immunoassay tests where the capture antibody is labeled with a chromagen, which allows for a positive reaction t ...

DESCRIPTION (provided by applicant): Despite the rise of bacterial resistance to antibiotics, the development of new antibiotics is on the decline. Methicillin-resistant Staphococcal aureus infections (MRSA) in the United States has been increasing, causing 19,000 deaths per year in the United States and contributing to 3 billion to 4 billion of additional annual health care costs. The issue of ...

DESCRIPTION (provided by applicant): Viscoelastic foam earplugs are commonly used for personal hearing protection to help reduce the incidence of hearing loss; however, many work environments exist where the protection from currently available earplugsis insufficient. In addition, the ability of existing foam earplugs to attenuate low frequency energy is relatively poor. Pilot experiments were ...

Hydraulic Artificial Urinary Sphincter - HydrAUS GT Urological, LLC. has prepared this NIH SBIR Phase I Grant Application entitled Hydraulic Artificial Urinary Sphincter - HydrAUS to detail goals and activities related to the design and development ofan implantable, hydraulic urinary sphincter intended to safely and effectively prevent urinary leakage in males and females suffering from Urin ...

DESCRIPTION (provided by applicant): The proposed study aims to evaluate the feasibility of applying Hypersonic Plasma Particle Deposition (HPPD) technique in regional coating Ti6Al4V used in orthopedic implants such that the surface modified region of HPPD coated Ti6Al4V is capable of being the articulating surface while the uncoated region remains ideal for bone and tissue in-growth. This is a ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics proposes to develop an ultra low power wireless electrocardiograph sensor for use in ambulatory electrocardiographs (ECGs). Ambulatory ECG products include traditional Holter recorders, cardiac arrhythmia event loop recorders, and recently introduced telemetry-enabled cardiac monitors that utilize cellular phone networks to provide ...

DESCRIPTION (provided by applicant): We propose to develop a contrast agent for photoacoustic imaging targeted to the receptors of vascular endothelial growth factor (VEGFR), so it can be accumulated and retained in tumor endothelial cells by VEGFR-mediated endocytosis. VEGFR are over expressed in angiogenic tumor vasculature from the very early stages of tumor development and therefore VEGFR imag ...

DESCRIPTION (provided by applicant): This SBIR project is designed to develop miniaturized cell-based biosensors for low cost, portability and enhanced shelf life by extending the viability of the cultured mammalian cells. We will demonstrate the benefit of our current technology by creating micro-chips with approximately 100 times smaller dimensions than the currently available Electrical Cell- S ...

DESCRIPTION (provided by applicant): The objective is to use a new innovative sensor technology called a Doppler velocimeter (DV) for solving the problem of wayfinding indoors for the vision impaired. By performing a Doppler measurement of the floor movement relative to the walking person it is possible to determine the along-track velocity, the cross-track velocity and the vertical (up or dow ...

DESCRIPTION (provided by applicant): The proposed SMART mount, a powered mounting and positioning system, provides individuals with significant disabilities access to and control over their immediate environment. It enables independent repositioning ofdevices by a person with little or no upper extremity function-from their bed or a wheelchair. With the SMART mount's ability to move, rota ...