Award Data

Agiltron is developing a new family of polymer-ceramic nanoparticle composite dielectric materials for high power capacitors such as required in directed energy pulsed systems. In Phase I we showed that embedding large dielectric constant fillers into nanodielctrics results in a composite with greatly improved breakdown strength and reduced dielectric loss compared to conventional materials. Our ...

We propose a novel poly-phase sampling scheme for an optoelectronic analog-to-digital converter (ADC) module which entails parallel sampling of different phases of an input RF signal to realize a 12-bit 10.24GSPS RF signal AD conversion. A unique feature of this approach is that electrical-in to electrical-out signal transfer is maintained for the optoelectronic sampling and demultiplexing circuit ...

Agiltron proposes to develop an infrared fiber having inherently attractive features of high wavelength conversion efficiency, wide wavelength-conversion bandwidth, and agile wavelength routing all in IR regions (2 ¡V 12 ƒYm). The design is closely coupled with our unique expertise in low loss IR chalcogenide fiber fabrication and IR photonics. The approach overcomes the difficulties associated ...

DESCRIPTION (provided by applicant): Molecule specific targeting and improving image contrast have been recognized as important research areas in cancer imaging. Goal of cancer diagnosis and prognosis research is to develop new imaging techniques to detect lesions with certainty in early stages so that they can be treated. Developing biomarkers, which will signal the presence and the type of lesio ...

DESCRIPTION (provided by applicant): This proposal outlines a body of research to evaluate the cytotoxicity and therapeutic efficacy of radiolabeled alpha-melanocyte stimulating hormone (a-MSH) peptide analogs that target a-particle emitting radioisotopes to the nuclei of melanoma cells. The selective targeting of alpha-particle emitting radioisotopes for cancer therapy is emerging as an exciting ...

DESCRIPTION (provided by applicant): NIH sponsored cancer researchers have been obtaining promising results using molecules radiolabeled with lead-212 in treatment for metastatic melanoma and disseminated colon and pancreatic cancers. Another isotope, radium-223 is being used in clinical trials in treatment of skeletal metastases. There is no effective therapy for these diseases. Together 199,280 ...

The Phase I STTR demonstrated major improvements in the deposition of high critical current YBCO films by a low-cost Metal Organic Deposition process on RABiTS substrates. A critical current of nearly 500 A/cm-width (77K, self-field) was achieved in a short length 2 m thick YBCO film, exceeding the Phase I goal of 450 A/cm-width. This performance is equivalent to a current of 200 A in an indus ...

DESCRIPTION (provided by applicant): Prostate cancer is the most prevalent cancer among men; and the second leading cause of cancer death among men in the US. There are currently no approved therapies for hormone-refractory prostate cancer. Epidemiological studies have demonstrated a strong relationship between incidence of and mortality from various cancers including prostate cancer, exposure to ...

Modern warfare is intensely information centric with vast amounts of information transmitted around the battlespace. Within this environment, it is critical to provide predictive and timely intelligence in planning and execution of operations. A tool is necessary to provide direction of ISR in the tasks of collection, exploitation, analysis, and dissemination. The tool resulting from this research ...

In organizations such as the Air and Space Operations Center (AOC), team members collaboratively process information about time sensitive targets for prosecution in time constrained situations. To assure the highest degree of performance, operators undergo periodic training. Training effectiveness is maximized by providing performance measurement and feedback to operators, so they can learn from t ...