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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. PPMP as a Ceramide Catabolism Inhibitor for Chemotherapy

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our goal is to develop 1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP) as a clinical inhibitor of ceremide catabolism, in order to enhance the anti-cancer activity of the cytotoxic retinoid, fenretinide (4-HPR). We have reported that 4-HPR increased ceramide in numerous pediatric and adult solid cancer and leukemia cell lines in vitro. We have also ...

    STTR Phase I 2003 Department of Health and Human Services
  2. Secure Interactive Telemedicine Via State-wide Internet

    SBC: AZ Technology Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The competitiveness of interactive telemedicine with alternatives is directly related to the cost of telecommunications services and equipment. The Integrated Services Digital Network (ISDN) used in the majority of interactive telemedicine systems has proven expensive and inflexible, resulting in limited deployment. Rapidly expanding Internet Protocol (IP) n ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. N/A

    SBC: AZ Technology Inc            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  4. N/A

    SBC: BEHAVIORAL SCIENCE CONSULTING, INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  5. Optimizing Hepatitis C virus NS5B Polymerase Inhibitors

    SBC: BIOCRYST PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The over-all objective of this project is identifying and developing selective nontoxic inhibitors of the hepatitis C virus NS5B polymerase and eventually testing them as therapeutics for chronic hepatitis C. At least four million people in the United States have chronic hepatitis C and the recent NIH Consensus Conference suggested that this number is actually ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Internet-based Alzheimer's Caregiver Support System

    SBC: Caregiver Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by investigator): The Iong-term objective of Small Business Innovative Research Phase I is to develop an Internet based Alzheimer's Caregiver Support System (iACSS). The iACSS would enable care to be provided remotely to individuals with Alzheimer's disease over the Internet. iACSS would feature a videoconferencing capability to communicate and monitor the Alzheimer's patien ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Rare Event Imaging

    SBC: Sciperio, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Rare-event imaging has profound implications for the early identification of potentially correctable terminal diseases, especially for cancer. What is required is a highly accurate "routine" test to be given to all patients, not just to those deemed at risk. This requires not only a highly accurate and repeatable process, but also a reasonably fast and inexp ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. N/A

    SBC: Diversified Scientific Inc            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  9. High Throughput Leukemia Diagnosis

    SBC: GENACO BIOMEDICAL PRODUCTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recurrent chromosome translocations in leukemias are useful cytogenetic markers for monitoring diagnosis, prognosis and treatment. Traditional cytogenetic study cannot recognize all the gene rearrangements at the molecular level. Also, it is a time consuming and labor intensive procedure. We have developed a proprietary technology that will allow high throughpu ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Parallel Assays for Anti-Ro Peptide Diagnostics

    SBC: JK AUTOIMMUNITY, INC.            Topic: N/A

    DESCRIPTION (provided by the applicant): Diagnosis of rheumatic diseases is inefficient, time consuming, and frustrating. Indeed, many patients suffer unnecessarily. We wish to develop a parallel assay system for the serology of autoimmune rheumatic diseases involving multiple analytes (on the order of 1,500 per assay performed) by concentrating upon the anti-Ro autoantibody system. Anti-Ro is as ...

    STTR Phase I 2003 Department of Health and Human Services

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