Award Data

ABSTRACT:Recent technical demonstrations in hostile fire sensing and classification have highlighted the use of costly cryogenically-cooled electro-optical sensors.While capable, these types of sensors come with a higher initial purchase price as well as high life cycle costs per platform.This activity will implement a broad area hostile fire sensing architecture that uses lower cost discrete sens ...

ABSTRACT:The objective of this proposal is to design an inexpensive hypersonic test article with an associated instrumentation package capable of providing measurements necessary for advancing the understanding of aerothermal behavior in the hypersonic flow regime. Significant advances and accuracy validation within multi-physics computational science and engineering (CSE) toolsets (such as comput ...

ABSTRACT: The Level of Impregnation (LOI) of resin in prepregged composite materials is critical to the quality and performance of finished Out-Of-Autoclave (OOA) composites.The widespread transition to OOA composites is reliant upon consistent material manufacture, which is jeopardized by the lack of a test methodology capable of accurately measuring LOI.Test techniques currently in practice are ...

ABSTRACT:The warfighter needs an accurate and reliable source of Position, Navigation, and Timing (PNT) when GPS is not available. Fortunately, technical advances in navigation sensors and algorithms can reduce dependence on the venerable, yet vulnerable, GPS system. Inertial sensors are becoming increasingly smaller and more accurate. Low cost, powerful embedded computing platforms enable real ti ...

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DESCRIPTION provided by applicant In nearly million new cancer cases are estimated to occur in the US where nearly two thirds will have treatment by radiation therapy In current clinical practice organ contour delineation on medical images is still performed with low levels of automation due to lack of highly automated commercial contouring software This deteriorates therapy plann ...

DESCRIPTION provided by applicant Influenza is a leading cause of death and morbidity in the US resulting in up to deaths hospitalizations and andgt $ billion in expenses per year Current antivirals incur high resistance rates and have low efficacy so there is a crucial need to develop better approaches to protect from seasonal influenza and future pandemics We aim to ...

DESCRIPTION provided by applicant Cognition Therapeutics Inc andapos s mission is to develop effective therapeutics for Alzheimerandapos s disease Recent scientific discoveries have identified oligomers of the brain protein Abeta as toxic culprits in the disease process Cognition has discovered therapeutic molecules that displace Abeta oligomers from neurons and block the downstream pathol ...

DESCRIPTION provided by applicant The emerging field of stem cell therapy has the potential to transform medicine forever However a major bottleneck for bringing stem cell therapies to the patient is the lack of adequate in vitro assays for the study of stem cell quality Critical test criteria are efficacy pluripotency prior to the differentiation process and safety lack of tumorigenicity ...

DESCRIPTIONprovided by applicantThe primary goal of this proposal is to develop and finalize configuration of a rapid molecular diagnostics test to predict antibiotic resistance of th major human uropathogensEscherichia coliKlebsiella pneumoniaeEnterobacter spp and Pmirabilisby determining the sub species clonal identityclonotypeof the infecting bacteria directly from urine samplesCurrentlythe emp ...