List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 5828 results
  1. Real-time Assessment of Antimicrobial Concentrations for Personalized Treatment of Infectious Diseases

    SBC: Nano Terra, Inc.            Topic: SB162-001

    There is an urgent need to optimize antimicrobial dosing in order to address the prevalence of drug-resistant pathogens and the increase of minimum inhibitory concentrations (MICs) of antimicrobials. Antimicrobials typically have a narrow window of effective concentration or therapeutic indices. If the drug is dosed above this concentration window it becomes toxic. Conversely, if under-dosed, trea ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  2. Real-time Assessment of Antimicrobial Concentrations for Personalized Treatment of Infectious Diseases

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: SB162-001

    This project will deliver, in Phase 1, aptamers build from an artificially expanded genetic information system (AEGIS) that bind to at least four of five antimicrobial targets: amphotericin, voriconazole, colistin, gentamicin, and meropenem. These aptamers will be shown in a prototype to bind these targets at relevant concentrations over a relevant dynamic range in 50 L blood samples. In Phase 2, ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  3. Point of Care Host-Pathogen Monitoring System

    SBC: Mbio Diagnostics, Inc.            Topic: SB162-002

    Septic shock is a significant worldwide health problem that affects millions, but is complicated to treat since many of the signs and symptoms are non-specific and common to other non-infectious sources of systemic shock. Patient care would be improved by a rapid test to monitor key biomarkers and determine whether antibiotic use is appropriate. We propose to deliver a quantitative, multiplexed ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  4. Point-of-Care technologies to monitor and characterize host-pathogen interactions during acute severe infection

    SBC: ProbiusDx Inc.            Topic: SB162-002

    In this SBIR proposal, ProbiusDx aims to develop a non-invasive, point of care diagnostic technology for characterizing host-pathogen interactions during acute infections afflicting warfighters within a resource-constrained setting; specifically we will develop a broad-spectrum platform to assay for multiple markers that define differing phases of progression in sepsis, beginning with the occurren ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  5. Platform for Research Optimization and Creation of Experiments in Social Science (PROCESS)

    SBC: Charles River Analytics, Inc.            Topic: SB162-003

    To better understand the world around them, social scientists develop models and theories of human behavior and interaction that they empirically test through a variety of quantitative and qualitative techniques. However, current methodological paradigms often introduce biases through sampling constraints and data analysis techniques that make the results of social science experiments hard to repl ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  6. Methods for Signal Isolation Across Heterogeneous Document Sets

    SBC: Thresher Ventures, LLC            Topic: SB162-003

    Text is a treasure trove of data for social, behavioral and economic researchers, for which the rapidly developing field of automated text analysis has produced numerous methods. However, the machine classifiers on which many of these methods depend degrade as data becomes noisier. Ad hoc approaches to reducing noisesuch as using analyst-generated keywords to collect documentscan introduce bias. D ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  7. Talaria- A Secure, Decentralized, Modular Transaction Architecture with an Unforgeable, Indelible, Transparent Ledger

    SBC: GALOIS, INC.            Topic: SB162-004

    Galois and Dan Boneh of Stanford offer Talaria, a research project and prototype architecture of a secure, decentralized messaging and transaction platform. Talaria addresses four concerns for such platforms: resilience, scalability, security, and transparency.Talaria uses a decentralized, redundant, and distributed server-side architecture to provide resiliency. Talaria provides scalability by us ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  8. Secure Messaging and Smart Transaction Platform based on Decentralized Ledger

    SBC: SAGUARO INNOVATION LLC            Topic: SB162-004

    The proposed research and commercialization efforts are aimed to solve some of the funda- mental performance and security challenges in decentralized ledger based messaging system and significantly move forward the industry and frontiers of messaging platform by providing solutions that achieve diverse functionalities, scalability, and high level security. The system uses a hybrid trust model and ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  9. Secure Messaging Platform

    SBC: WICKR INC.            Topic: SB162-004

    To meet the unique messaging, data-sharing and transaction processing needs of DARPA and ultimately other parts of DoD, the Wickr solution will leverage our proven encryption technology to develop a scalable, decentralized messaging and transaction solution that will support DARPA's and DoD's needs in a number of environments and platforms. At a minimum, the solution to DARPAs messaging and data s ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency
  10. SIMBA: Secure Messaging on the Blockchain Architecture

    SBC: INDIANA TOOL & MFG. CO., INC.            Topic: SB162-004

    The secure messaging on a Blockchain architecture (SIMBA) project will architect and design a decentralized mobile peer-to-peer, end-to-end, secure messaging application that uses Blockchain technology. We aim to build SIMBA from the Fabric (Open Blockchain) implementation due to its novel approach to smart contracts using chaincode services and several other features including membership, consens ...

    SBIR Phase I 2017 Department of DefenseDefense Advanced Research Projects Agency

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government