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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Tomographic Nanoscopy for Pathogen Identification

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: CBD171-003

    This effort will augment the capabilities of an existing all reflecting, confocal FTIR microscope to allow for digital holographic imaging as wellspectral content determination at video frame rates. The use of a dual beam frequency comb, with a beam path coincident with the pathrequired for the digital holographic imaging, will allow spectral determination of any organism being holographically ima ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Process Development and Manufacture of an Antibody-based Therapy Against Sudan EbolaVirus

    SBC: BIOFACTURA, INC.            Topic: CBD171-005

    Recently we have observed a massive outbreak of Ebola virus. This family of virus causes a significant bioterrorism threat due to the high levelof mortality, rate of transmissibility and the lack of an approved vaccine or therapy directed against it. The goal of this proposal is to develop,optimize and scale-up a mammalian cell culture-based bioprocess for the rapid manufacture of an antibody-base ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Signal Processing for Layered Sensing

    SBC: TOYON RESEARCH CORPORATION            Topic: CBD152-006

    As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable of confirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR) sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  4. Concurrent identification of Natural Antibiotics-Producing Gene Clusters and Culture Conditions

    SBC: Carrera Bioscience Inc.            Topic: CBD152-004

    Modern metagenomics studies on diverse microbiomes revealed immense repertoires of potential natural products/antibiotics to be tapped into. However, identifying such secondary metabolites (SMs) directly from a complex microbiome remains rarely successful due to two major technical challenges: i) difficulty in dissecting complex microbiome samples and massive metagenomics data, and ii) difficult ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  5. Contaminated Material Encapsulation Technology for Transportation

    SBC: TDA Research, Inc.            Topic: CBD161-006

    The United States Department of Defense (DOD) requires a container for the safe transportation of chemically or biologically contaminated materials, in accordance with DOD, federal and international standards. These materials must be packaged in a manner so that they arrive at their destination in good condition and without presenting a hazard to nearby persons during transport. The packaging re ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  6. Selection of blood-brain barrier penetrating single domain antibodies as medial countermeasures for viral induced encephalitis

    SBC: GUILD ASSOCIATES, INC.            Topic: CBD161-004

    Alphaviruses pose significant risks to warfighters where encephalitic virus infection can lead to death. There is no effective treatment for alphavirus induced encephalitis and countermeasures are of high importance. Single domain antibodies (sdAb) are low molecular weight engineered antibody fragments composed of a single heavy-chain variable domain which have proven easier to manipulate and re-e ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  7. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152-004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using a metagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms, like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, culti ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. Self-Decontaminating Textiles

    SBC: Luna Innovations Incorporated            Topic: CBD161-001

    Luna Innovations is addressing the need to develop novel fluid repellent textile treatments for military uniforms that will actively decontaminate chemical and biological warfare agents (CBWA). There have been recent significant advances in textile treatments that have demonstrated water, oil and chemical agent resistance that are superior to Quarpel repellent treatments currently used on protect ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Automated Visual Anthropometry for Three-Dimensional Assessment of Respirators (AVATAR)

    SBC: Charles River Analytics, Inc.            Topic: CBD161-005

    Military respirator masks provide the Warfighter with life critical protection against chemical, biological, radiological, and nuclear (CBRN) threats. To ensure the safety, comfort, and effectiveness of the American Warfighter, it is essential that every Warfighter be assigned a respirator that is properly sized and fitted. However, current methods for sizing and fitting respirators depend on manu ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  10. Protective Mask Sizing App

    SBC: CFD Research Corporation            Topic: CBD161-005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometric measurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed software app aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D im ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense

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