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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Adjustable Focus Lenses for Respiratory Protection

    SBC: Voxtel, Inc.            Topic: CBD152-001

    A low-cost, adjustable optical-correction technology will be developed for integration with AVON M50 respiratory protective masks, allowing for fast, adjustable vision correction. Variable-focus lenses will be designed using 3D freeform gradient index materials, which allow both optical power and geometric and chromatic aberrations corrections to be achieved in planar films. A Phase I prototype ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Novel Smart Split Neck Seals for Respiratory Protection

    SBC: TRITON SYSTEMS, INC.            Topic: CBD152-002

    This development is to address the current limitation in respiratory protection neck seal designs. The developed system will allow for a smart split neck seal design that allows for donning versatility, improved comfort, and will provide feedback to the user regarding seal performance. The application of smart technology will help balance comfort with protection in ensuring that a hermetic neck ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  3. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152-004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using a metagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms, like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, culti ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  4. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: iXpressGenes Inc.            Topic: CBD152-004

    Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing data will cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters (BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  5. Concurrent identification of Natural Antibiotics-Producing Gene Clusters and Culture Conditions

    SBC: Carrera Bioscience Inc            Topic: CBD152-004

    Modern metagenomics studies on diverse microbiomes revealed immense repertoires of potential natural products/antibiotics to be tapped into. However, identifying such secondary metabolites (SMs) directly from a complex microbiome remains rarely successful due to two major technical challenges: i) difficulty in dissecting complex microbiome samples and massive metagenomics data, and ii) difficult ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  6. High Sensitivity, Low Complexity, Multiplexed Diagnostic Devices

    SBC: Paratus Diagnostics            Topic: CBD152-005

    Infectious diseases have been a constant cause of non-battlefield injury and illness for military personnel engaged in operations throughout the world. Detection of these infectious pathogens is critical to proper patient care and management of outbreaks, yet many existing diagnostic tests fail to provide adequate sensitivity and/or simplicity for use in forward locations or in isolated areas. W ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  7. Innovative concept for detection and identification of biological toxins

    SBC: Daktari Diagnostics, Inc.            Topic: CBD152-005

    The focus of this SBIR proposal is to demonstrate rapid, multiplexed detection of acute bacterial and viral pathogens of global importance on a single test platform. Daktaris microfluidic immunoassay platform, under development since 2009 for HIV and hepatitis C (HCV) applications, is capable of femtomolar detection of bacterial and viral antigens consistent with needs for infectious disease dia ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. Wavelet-Based Approach for Signal Processing and Analysis

    SBC: Physical Optics Corporation            Topic: CBD152-006

    To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operational pictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing and Analysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data availabl ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Multi-source Aggregation (fusion) of Semantic Tiered Data (MAST)

    SBC: Modus Operandi, Inc.            Topic: CBD152-006

    Existing approaches for the multi-sensor data correlation for chemical and biological defense fail to provide timely and accurate situational awareness capabilities in the presence of complex CBRN attack scenarios. Toward the maintenance of a common operating picture for situational awareness, innovations are required to fuse signature feeds from networked chemical/biological (CB) and non-CB sen ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  10. Signal Processing for Layered Sensing

    SBC: Toyon Research Corp.            Topic: CBD152-006

    As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable of confirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR) sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense

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