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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IMPROVING MANUFACTURING AND POTENCY OF CRYOPRESERVED MALARIA SPOROZOITE VACCINE

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The development of Sanaria's aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoite (SPZ)-based products has received international recognition during the past year, due principally to four findings: 1)PfSPZ Challenge (infectious PfSPZ) induced malaria in volunteers, 2) PfSPZ Vaccine (radiation attenuated PfSPZ) induced unprecedented levels ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  2. Transgenic Mosquitoes for Improved Malaria Sporozoite Vaccine Manufacture

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): An ideal tool for eliminating Plasmodium falciparum (Pf), the causative agent of 99% of all malaria deaths, would be a highly effective vaccine that prevents blood stage infection and thereby prevents both disease and transmission. Sanaria's goal is to develop and commercialize a Pf sporozoite (SPZ) vaccine that prevents Pf blood stage infection in gt 90% ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. N-Methanocarbathymidine (N-MCT) for the treatment of herpes and pox virus infecti

    SBC: N&N Pharmaceuticals, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): Diseases associated with the Poxviridae (smallpox, vaccinia and cowpox viruses), and Herpesviridae (HSV-1, HSV-2, HSV-8, VZV, EBV) dsDNA viruses represent major worldwide public health problems. NandN Scientific, Inc. (NandN) is developing a first of its class broad-spectrum orally bioavailable antiviral drug, N- methanocarbathymidine (N-MCT), which has exhibit ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Small Molecules as Antiprotozoal Agents

    SBC: RADIX PHARMACEUTICALS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The proposed research focuses on the development of novel therapeutic agents for the prevention and treatment of malaria caused by P. falciparum. A previous Phase I project has discovered novel molecules with potent antimalarial activity against both sensitive and multidrug resistant malaria strains in some in vitro and in vivo models. Lead compounds are low in ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Device to Improve Treatment of Colorectal CA using O2 Dependent Phosphorescence

    SBC: SURGISENSE CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Standard of care for surgical resection of rectal cancer is the performance of low anterior resection (LAR). After removal of the cancerous segment, a surgical stapler is used to restore continuity by creating an anastomosis between the resulting ends of disjointed bowel. Anastomotic leak is one of the most dreaded complications of colorectal surgery due to the ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. A Tool for Supporting and Monitoring Decision Making in ADHD

    SBC: CHADIS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): This proposal is to complete and validate a new web-based tool to assist in the screening, diagnosis and management of mental health disorders (focusing here on ADHD), quality improvement (QI) documentation and efficient large scale research. CHADIS is a screening, assessment and decision support system delivering tools online for care of health, development, a ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. SpeedShop Ease of use Performance Analysis for Heterogeneous Processor Systems

    SBC: ARGO NAVIS TECHNOLOGIES, LLC            Topic: 02b

    We propose to build on the Open|SpeedShop modular, extensible architecture and existing capabilities to examine the feasibility of providing seamless, integrated heterogeneous processor performance analysis support, focusing on GPU processors. Accelerators such as GPUs are becoming increasingly important at HPC laboratories within the DOE. However, the ability of tools to succinctly con ...

    SBIR Phase I 2012 Department of Energy
  8. Multiscale Two-Phase Bubbly Flow Modeling

    SBC: DYNAFLOW, INC.            Topic: 38a

    Multiphase bubbly mixture flows are of importance in turbomachinery, pipelines, cooling systems, reaction towers, as well as in various applications in petroleum, chemical, geothermal, and nuclear industries. The presence of the gaseous component has a strong influence on performance and efficiency. The ability to predict the flow behavior accurately is essential in designing energy efficient two- ...

    SBIR Phase II 2012 Department of Energy
  9. Development of an Acoustic Instrument for Bubble Size Distribution Measurement in Mercury

    SBC: DYNAFLOW, INC.            Topic: 09c

    Intense pulsed pressure waves induced by proton beam impact on mercury in a spallation target propagate in the mercury and reflect from vessel walls as expansion waves resulting in cavitation damage to the walls. Injection of gas bubbles (few micrometer diameter range and void fraction of the order of 1%) into the mercury flow is one of the promising methods under investigation to mitigate the dam ...

    SBIR Phase I 2012 Department of Energy
  10. Process Intensification by Integrated Reaction and Distillation for Synthesis of Bio-Renewable Organic Acid Esters

    SBC: E3TECSERVICE, LLC            Topic: 10b

    Organic acid esters, produced from bio-based organic acids and alcohols, are truly bio-renewable, green chemicals that are promising replacements for halogenated and other petroleum-based solvents, lubricants, and plasticizers. With current uncertainty regarding the future of ethanol and other alcohols as biofuels, and with the availability of organic acids via fermentation, there exists strong mo ...

    SBIR Phase I 2012 Department of Energy
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