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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Technology to Disseminate WOOP (Wish, Outcome, Obstacle, Plan) to Dementia Caregivers

    SBC: BORROW MY GLASSES LLC            Topic: NIA

    1 Approximately 6.5 million Americans aged 65 and older live with dementia, supported by more than 11 million2 unpaid family caregivers. These numbers are projected to rise exponentially in the coming decades fueling the3 need to develop scalable ways to support dementia caregivers. The need to empower dementia caregivers to4 continue providing care while maintaining their own health and well-bein ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Engineering next generation supercharged CAR T-cells against solid tumors

    SBC: Cellinfinity Bio, Inc.            Topic: 102

    Project summary Adoptive cell therapy has revolutionized cancer treatment and has immense potential to cure a variety of cancer types. Multiple critical barriers exist for current CAR-T therapy particularly in solid tumor, including insufficient T cells trafficking to the cancer site, lack of effective cancer cell killing, severe toxicity, strong immunosuppression in the tumor microenvironment, an ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR Phase I: Antibody Therapy that Targets Neoantigens in Acute Myeloid Leukemia via the Antibody Dependent Cell-mediated Cytotoxicity Mechanism of Natural Killer Cells

    SBC: ENABLE LIFE SCIENCES LLC            Topic: PT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project focuses on the unique combination of cancer-specific antibodies and adoptive Natural Killer (NK) immune cells needed to offer personalizable cancer therapies.This innovation represents a platform technology that can spawn multiple innovative cancer treatments, which could positively impact lif ...

    SBIR Phase I 2023 National Science Foundation
  4. SBIR Phase I: Software-Defined Networking and Resource Virtualization in Low Earth Orbit (LEO) Satellite Constellations

    SBC: UNINET LLC            Topic: SP

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the extension of state-of-the-art terrestrial 5G technologies to non-terrestrial satellite networks. Non-terrestrial networks (NTNs) are the ideal hosts for many commercial applications involving monitoring, reconnaissance, and remote sensing such as agricultural planting, remote factory op ...

    SBIR Phase I 2023 National Science Foundation
  5. PANK Activators for the treatment of pantothenate kinase-associated neurodegeneration

    SBC: Virtus Therapeutics Corporation            Topic: NINDS

    SUMMARY Pantothenate kinase-associated neurodegeneration, PKAN, is a rare progressive neurodegenerative disorder associated with iron accumulation in the brain. The disease causes early immobility and often death by early adulthood. PKAN is caused by mutations in one of four human pantothenate kinase genes, PANK2 gene, which encodes a mitochondrial pantothenate kinase. Consistent with the clinical ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a sample preparation protocol for 3D kidney ultrastructural analysis and immunolabeling by light microscopy

    SBC: panluminate Inc.            Topic: 400

    Abstract The success of cohort studies such as the NIDDK Kidney Precision Medicine Project (KPMP) with its massive amount of samples depends on the cost and time-efficient evaluation of kidney biopsies at multiple scales. Assessing the structure of kidney tissue at the nanoscale (~10 nm) and evaluating the 3-D distribution of protein biomarkers in that context is, however, currently severely limit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Expeditionary Virtualized Training Unit for Undersea Warfare Decision Support System (USW-DSS)

    SBC: SONALYSTS INC            Topic: N231044

    Sonalysts, Inc. (Sonalysts) proposes a portable expeditionary unit that can deliver Undersea Warfare Decision Support System (USW-DSS) training to the Fleet via an orchestrated containerized system with an integrated training management application to track operator completion and launch training content. Sonalysts’ solution will also include Artificial Intelligence/Machine Learning (AI/ML) base ...

    SBIR Phase I 2023 Department of DefenseNavy
  8. Development of an endometrial ablation drug-device combination to treat heavy menstrual bleeding

    SBC: GYNION, LLC            Topic: NICHD

    PROJECT SUMMARY Over 10 million women in the US and 100 million women globally suffer from Heavy Menstrual Bleeding (HMB). Oral medications lack effectiveness and, like hormonal IUDs (intrauterine devices), have significant side effects. Currently available endometrial ablation options, which is another therapeutic alternative, are complex and require advanced anesthesia, which significantly limit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Perennix Mobile Standalone Asset Management System Feasibility Study

    SBC: Perennix. LLC            Topic: AF2310022

    The WCH serious gaming solution can close the gap between DoD civilian healthcare employees and the active-duty/retiree community they serve. By fostering a safe learning environment, culturally sensitive communication skills, and willingness to learn fro

    SBIR Phase I 2023 Department of DefenseAir Force
  10. A Self-Guided Mobile Intervention for Adults with Binge Eating and Obesity

    SBC: OUI THERAPEUTICS INC            Topic: 104

    ABSTRACT Obesity and comorbid binge eating are serious health problems for more than 40% of adults across the US.7 Health complications due to obesity comprise more than 20% of the nation’s healthcare budget, and the healthcare costs of individuals with binge eating are $18,152 higher than in obese peers without binge eating.13 The prevalence of binge eating and the substantial burden of healthc ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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