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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR Phase I: Antibody Therapy that Targets Neoantigens in Acute Myeloid Leukemia via the Antibody Dependent Cell-mediated Cytotoxicity Mechanism of Natural Killer Cells

    SBC: ENABLE LIFE SCIENCES LLC            Topic: PT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project focuses on the unique combination of cancer-specific antibodies and adoptive Natural Killer (NK) immune cells needed to offer personalizable cancer therapies.This innovation represents a platform technology that can spawn multiple innovative cancer treatments, which could positively impact lif ...

    SBIR Phase I 2023 National Science Foundation
  2. SBIR Phase I: Software-Defined Networking and Resource Virtualization in Low Earth Orbit (LEO) Satellite Constellations

    SBC: UNINET LLC            Topic: SP

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the extension of state-of-the-art terrestrial 5G technologies to non-terrestrial satellite networks. Non-terrestrial networks (NTNs) are the ideal hosts for many commercial applications involving monitoring, reconnaissance, and remote sensing such as agricultural planting, remote factory op ...

    SBIR Phase I 2023 National Science Foundation
  3. Development of a sample preparation protocol for 3D kidney ultrastructural analysis and immunolabeling by light microscopy

    SBC: panluminate Inc.            Topic: 400

    Abstract The success of cohort studies such as the NIDDK Kidney Precision Medicine Project (KPMP) with its massive amount of samples depends on the cost and time-efficient evaluation of kidney biopsies at multiple scales. Assessing the structure of kidney tissue at the nanoscale (~10 nm) and evaluating the 3-D distribution of protein biomarkers in that context is, however, currently severely limit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Engaging the Manufacturing Industrial Base in Support of DLA’s Critical Supply Chains (DLA232-001)

    SBC: Beacon Industries, Inc.            Topic: DLA232001

    Coupling, Shaft is a mechanical component used to connect two rotating shafts together, allowing the transmission of power and torque. It helps to minimize the effects of misalignment, vibration, and shock and reduces the stress and wear on the connected shafts and their bearings. The Coupling, Shaft (NSN 3010-01-679-7883) listed in Small Business Innovation Program website is an aviation critical ...

    SBIR Phase I 2023 Department of DefenseDefense Logistics Agency
  5. PANK Activators for the treatment of pantothenate kinase-associated neurodegeneration

    SBC: Virtus Therapeutics Corporation            Topic: NINDS

    SUMMARY Pantothenate kinase-associated neurodegeneration, PKAN, is a rare progressive neurodegenerative disorder associated with iron accumulation in the brain. The disease causes early immobility and often death by early adulthood. PKAN is caused by mutations in one of four human pantothenate kinase genes, PANK2 gene, which encodes a mitochondrial pantothenate kinase. Consistent with the clinical ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of an endometrial ablation drug-device combination to treat heavy menstrual bleeding

    SBC: GYNION, LLC            Topic: NICHD

    PROJECT SUMMARY Over 10 million women in the US and 100 million women globally suffer from Heavy Menstrual Bleeding (HMB). Oral medications lack effectiveness and, like hormonal IUDs (intrauterine devices), have significant side effects. Currently available endometrial ablation options, which is another therapeutic alternative, are complex and require advanced anesthesia, which significantly limit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. IL-17A mRNA-targeted oligonucleotide therapeutics in Idiopathic Pulmonary Fibrosis (IPF)

    SBC: TARGETSITE THERAPEUTICS CORPORATION            Topic: NHLBI

    Abstract. Idiopathic pulmonary fibrosis (IPF) is a progressive fibroproliferative disorder affecting ∼3 million people worldwide with function-limiting progressive symptoms and a 2-3 year median survival time from diagnosis. While the etiology of IPF is not clear, genetic factors, environmental exposures and microbial pathogens have been identified as IPF risk factors. Pirfenidone and nintedanib ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Technology to Disseminate WOOP (Wish, Outcome, Obstacle, Plan) to Dementia Caregivers

    SBC: BORROW MY GLASSES LLC            Topic: NIA

    1 Approximately 6.5 million Americans aged 65 and older live with dementia, supported by more than 11 million2 unpaid family caregivers. These numbers are projected to rise exponentially in the coming decades fueling the3 need to develop scalable ways to support dementia caregivers. The need to empower dementia caregivers to4 continue providing care while maintaining their own health and well-bein ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Secondary Emission Detector Modules for High Energy Physics Experiments

    SBC: NVIZIX LLC            Topic: C5637a

    We propose simulating and constructing a prototype and demonstration brassboard of a Secondary Emission Sensor Module (SESM) for ionizing radiation, as a proof of principle and guide to Phase II and beyond. The simulation and design studies will guide module construction and point to future uses. The module is anticipated to have ~30 stages of sheet dynode with an areal size ~15x15 cm. It will be ...

    SBIR Phase I 2023 Department of Energy
  10. Bifunctional nanocatalyst for one step drop-in diesel production using biomass derived syngas

    SBC: 3D ARRAY TECHNOLOGY LLC            Topic: C5610c

    C56-10c-273795The proposed SBIR phase I project aims to develop an energy-efficient and sustainable bifunctional nanoarray-based catalyst system that coherently integrates syngas-to-wax hydrocarbons and wax hydrocarbons-to-diesel fuel conversions in a tandem one-step catalytic process for biomass-derived syngas conversion into drop-in transportation hydrocarbons with low aromatic, oxygen, sulfur a ...

    SBIR Phase I 2023 Department of Energy
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