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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Antibacterial Agents That Target DNA Replication in Mycobacterium tuberculo

    SBC: Achillion Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis (MTB) is probably the most ubiquitous microbial pathogen in the world today infecting one-third of the total population and causing millions of active tuberculosis (TB) cases each year. The economic costs are substantial and more than one million people die of TB infections each year. Before the arrival of antimicrobial therapy, TB wa ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments

    SBC: AFFOMIX, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In the to-be-developed method: i) a set of antibodies directed against specific DNA-binding proteins are uniquely bar-coded with a DNA 'ZipCode;' ii) ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. High-throughput screening and identification of scFv antibodies against glycosyla

    SBC: AFFOMIX, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of affinity screening process based on emulsion, secretion, and capture, which we term ESCape . In the proposed phage ESCape method, E. coli transfo ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. A bifunctional antibody screening system for both phage display and yeast two-hyb

    SBC: AFFOMIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a wide-variety of disorders. We propose to develop a means of making the discovery of immunotherapeutics faster ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Ultrahigh Definition Microdisplay (UDM)

    SBC: ALCES Technology, Inc.            Topic: AF093021

    Advanced helmet-mounted displays (HMD) have been proven to improve the safety and success rate of warfighters in combat situations. These HMD systems provide pilots and warfighters with enhanced situational awareness and augment their abilities to fulfill their mission objectives. However, current systems are limited in display resolution, bit depth, and refresh rates. To maintain a strategic adva ...

    SBIR Phase I 2010 Department of DefenseAir Force
  6. Environmentally Constrained Naval Search Planning Algorithms

    SBC: APPLIED MATHEMATICS, INC.            Topic: N101048

    The Undersea Warfare Decision Support System (USW-DSS), currently employed by Carrier Strike Groups for integrated command and control and anti-submarine warfare (ASW), uses the Operational Route Planner (ORP) that incorporates a genetic algorithm to define optimal ASW search tracks. This capability does not currently consider route planning and supporting ASW operations in the context of avoiding ...

    SBIR Phase I 2010 Department of DefenseNavy
  7. Development of Magnetostrictive Energy Harvesting of Mechanical Vibration Energy

    SBC: Applied Physical Sciences Corp.            Topic: N10AT020

    Applied Physical Sciences and the University of Maryland propose to develop a magnetostrictive transducer that harvests electrical energy from shipboard machinery while simultaneously suppressing vibration to improve the ship’s stealth characteristics and thereby improving the performance of hull mounted sonar systems. Analysis performed during the Base Effort will provide an initial design spec ...

    STTR Phase I 2010 Department of DefenseNavy
  8. External Pipe Sound Pressure Level Sensor

    SBC: Applied Physical Sciences Corp.            Topic: N10AT016

    Applied Physical Sciences (APS) and the Pennsylvania State University Applied Research Laboratory (ARL/PSU) will collaborate in the development of a novel sensor system to measure the low frequency acoustic pressures within a fluid-filled pipe. The proposed concept improves upon the Navy’s current Array Based Acoustic Measurement (ABAM) system for laboratory characterization of full-scale piping ...

    STTR Phase I 2010 Department of DefenseNavy
  9. High Gain Array of Velocity Sensors

    SBC: Applied Physical Sciences Corp.            Topic: N101014

    Applied Physical Sciences as the prime contractor and Undersea Sensor Systems, Inc. as the subcontractor propose an innovative approach to develop an air-deployed sonobuoy system having an array gain of at least 24 dB. The approach involves an array of subminiature vector sensors coupled to sophisticated in-buoy signal processing algorithms designed to provide the requisite data compression so tha ...

    SBIR Phase I 2010 Department of DefenseNavy
  10. Automated Data Recording Technology for Assessing Parachute Performance and Use

    SBC: Applied Physical Sciences Corp.            Topic: A09163

    Applied Physical Sciences Corp. (APS) in collaboration with Capewell Inc. will develop an automated system for logging parachute usage and performance electronically using a miniature embedded data logger which interfaces directly with commercial-off-the-shelf (COTS) radio frequency identification (RFID) readers. The proposed system is intended to replace parachute logbooks with a small, removable ...

    SBIR Phase I 2010 Department of DefenseArmy
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