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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Clinical and Non Clinical Evaluations of repeat administrations of the FAST PV and mGFR Technology

    SBC: PHARMACOPHOTONICS, INC.            Topic: 400

    DESCRIPTION provided by applicant Pharmaco Photonics DBA FAST Biomedical proposes a PHASE IIB project to determine the safety and functionality of repeat administration of the FAST PV and mGFR Technology in both non clinical and clinical studies The long term goal of this SBIR project is to test FASTandapos s fluorescent based test in humans and commercializes this product for rapid detecti ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Novel treatment of posttraumatic stress disorder

    SBC: ANAGIN            Topic: 101

    Project Summary The present applicationNovel Treatment for Posttraumatic Stress Disorderaddresses the critical need for more efficacious treatments for posttraumatic stress disorderPTSDThe excitatory neurotransmitterglutamateactivates a key neural signaling cascade upon a trauma experienceIn this activationglutamate binds to and activates the NMDA receptora glutamate receptor subtypeBinding and ac ...

    SBIR Phase II 2017 Department of Health and Human Services
  3. Electrical System for Rapidly Detecting Viable Bacteria in Blood Culture

    SBC: TECHSHOT, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Background Each year in the US there are over Million Blood Cultures performed to determine the presence absence of viable microorganisms in the blood of patients suspected of having Blood Steam Infection BSI or Septicemia Current technology for Blood Cultures typically takes days to provide a result Our proposed system would enable the user to obt ...

    SBIR Phase II 2014 Department of Health and Human Services
  4. Magnetic Flow Sorter for Pancreatic Islet Isolation

    SBC: TECHSHOT, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Techshot, Inc. has successfully completed SBIR Phase I and Phase II research demonstrating that magnetically labeled porcine islets of Langerhans can be isolated from contaminating exocrine tissue by flow sorting usinga quadrupole magnetic separator ( Quadrasep ) designed for that purpose. Magnetically sorted islets are superior in morphology and physiology to ...

    SBIR Phase II 2013 Department of Health and Human Services
  5. Magnetic Flow Sorter for Pancreatic Islet Isolation

    SBC: TECHSHOT, INC.            Topic: 200

    DESCRIPTION provided by applicant Techshot Inc has successfully completed SBIR Phase I and Phase II research demonstrating that magnetically labeled porcine islets of Langerhans can be isolated from contaminating exocrine tissue by flow sorting using a quadrupole magnetic separator andquot Quadrasepandquot designed for that purpose Magnetically sorted islets are superior in morphology and ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Prebiotic Fiber as Targeted Dietary Management of Irritable Bowel Syndrome

    SBC: NUTRABIOTIX, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The objective of this Phase II SBIR application is to test NTX-1 fiber in patients with constipation-predominant IBS (IBS-C) and determine if it can reduce symptoms, beneficially modify gut microbiota composition, and improve gut milieu in these patients. Our hypothesis for the Phase II study is that NTX-1 fiber is better tolerated (i.e. has less side effects) ...

    SBIR Phase II 2013 Department of Health and Human Services
  7. Determining Cardiovascular Health Using High-Throughput Comparative Proteomics

    SBC: PREDICTIVE PHYSIOLOGY AND MEDICINE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The Phase II work proposed here involves the high-throughput proteome profiling of molecules associated with cardiovascular disease. Comparative profiling of disease-relevant species will lead to a marketable product - the PPM Cardiovascular Health and Wellness Report. Molecular profiling is accomplished using novel IMS-MS instrumentation and a three-minute an ...

    SBIR Phase II 2008 Department of Health and Human Services
  8. Tin Whisker Mitigation Technologies for Sn-based Surface Finishes on Electronic Assemblies and Microelectronic Devices

    SBC: Foresite, Inc.            Topic: MDA08T010

    The impact of metal whiskers on the reliability of electronics has been exacerbated by environmentally-driven efforts to eliminate lead from tin plating and solders. Even exempt applications, such as military, are affected due to COTS. Foresite, Inc., a consultant, laboratory and test equipment development company, has a goal for the subject research, in collaboration with Purdue University, to ...

    STTR Phase II 2010 Department of DefenseMissile Defense Agency
  9. In vivo Thermoacoustic Imaging of HER2 Status

    SBC: OPTOSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Fast Track application, we propose developing the novel imaging technology and molecular probe that will enable the non-invasive detection and quantification of HER2 overexpression in breast cancers. The approach we are promoting is to label Herceptin, a therapeutic mono-clonal antibody, with an infraredabsorbing dye, and then to detect the presence ...

    SBIR Phase II 2006 Department of Health and Human Services
  10. A Noninvasive Sensor/Control Suite for Health Monitoring and Extended Life of Aircraft Generation Systems

    SBC: P C KRAUSE AND ASSOCIATES INC            Topic: N06T007

    Catastrophic failures in aircraft electrical power systems can compromise the readiness, safety, and capabilities of the war-fighter. In this effort, a multi-physics suite of tools will be developed based upon the successful Phase I research to provide a comprehensive prognostics and health management system (PHM) for aircraft generators and associated electrical systems. The PHM will be based upo ...

    STTR Phase II 2008 Department of DefenseNavy

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