List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Submarine Shipboard Power Supply Bridge

    SBC: P C KRAUSE AND ASSOCIATES INC            Topic: N171075

    The objective of this effort is to construct and test a 40 kW UPS with at least 100ms of holdup time, integrated into a standard 19 inch rack mount enclosure with 4U (7 inch) height, and designed to meet electrical and mechanical/shock specifications required for naval shipboard application. Traditional UPS applications are typically not optimized for weight and volume, and utilize bulky lead-acid ...

    SBIR Phase II 2019 Department of DefenseNavy
  2. Black Box RF Sat-Link for Mission Success, Risk Mitigation, and Space Debris

    SBC: NearSpace Launch            Topic: AF183005

    The proposed Phase 2 NSL Black Box is a redundant radio link connected through the $2B Globalstar commercial Sat-phone constellation and a timely AF Dual-Purpose Technology. The miniaturized and autonomous Black Box (BB) solution with its 24/7 global coverage (latency of seconds) can greatly increase performance and response, reduce risk, and help with orbital debris tracking. The Black Box techno ...

    SBIR Phase II 2019 Department of DefenseAir Force
  3. Open Call for Innovative Defense-Related Dual-Purpose Technologies/Solutions with a Clear Air Force Stakeholder Need (RAPID)

    SBC: Trek10 Inc.            Topic: AF183005

    Legacy Air Force IT systems behind the Operational Training Infrastructure (OTI) are inhibiting warfighter readiness due to lack of interoperability and flexibility, high costs, and need for manual processes. Next generation cloud computing that focuses on cloud-native, serverless designs will enable the Air Force to embrace agility, security, scalability, and lower costs to modernize the OTI.Trek ...

    SBIR Phase II 2019 Department of DefenseAir Force
  4. Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager

    SBC: Aeon Imaging, LLC            Topic: W

    Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human Services
  6. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This applicationDevelopment of novel small molecule analgesics modulating the nNOS NOS AP proteinprotein interactionaddresses the critical need for more effective medications to treat chronic neuropathic pain affectingmillion people in the United StatesCurrent pain medications such as NSAIDSsteroidsopiates and gabapentin analogs have documented and often severe side effectsare poorly effe ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Novel therapeutic approach in treatment of glioblastoma using sustained delivery of Connxin43 carboxy-terminal peptide encapsulated in biodegradable nanoparticles in combination with temozolomide

    SBC: FirstString Research, Inc            Topic: 102

    PROJECT SUMMARY GlioblastomaGBMis an incurable cancer even with aggressive therapies such as surgical resection followed by radiotherapy and chemotherapy using temozolomideTMZEfforts to improve surgical resection or the efficacy of irradiation are limited by the potential damage these interventions cause to the brainIn contrastsensitizing GBM to TMZ is an appealing strategy because TMZ has excelle ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Development of new anti-epilepsy treatments targeting cellular energetics through mitochondrial modulation with optimal pharmacokinetics and toxicity profiles

    SBC: Neuroene Therapeutics, LLC            Topic: 105

    Neuroene Therapeutics is a biotech company established to develop and commercialize safe effective therapies for epilepsyinpeople develop epilepsy in their lifetimehowever the currently available antiepileptic drugsAEDshave several issues and liabilities that leave unmet market needssuch asnot controlling seizures forof patients with epilepsycurrent AEDs only treat the symptoms of epilepsy and do ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Optical Device for Sorting Particles by Size

    SBC: En'urga Inc.            Topic: NA

    This Phase II SBIR project will continue the development of an optical sorter that will be used to estimate drop sizes in sprays. The optical sorter will determine the size of drops in the 0.1 to 10 microns range. Drops in this size range are prevalent in the automobile industry, where the fuel injection pressures have increased tremendously over the past two decades. These newer injectors provide ...

    SBIR Phase II 2018 Department of CommerceNational Institute of Standards and Technology
  10. Rational Design of sub-100 nm Polystyrene Particles with a Low Coefficient of Variation in Size

    SBC: Tetramer Technologies,L.L.C.            Topic: NA

    During this Phase II SBIR development program, Tetramer Technologies will develop highlymonodisperse 100-nm and sub-100-nm diameter nanoparticles for use as latex size standards. Highlymonodisperse nanoparticle latexes are needed for improved calibration of electron microscopes, lightscatteringparticle sizing instruments, atomic force microscopes, and particle counters/contamination monitors used ...

    SBIR Phase II 2018 Department of CommerceNational Institute of Standards and Technology

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government