Award Data

Malaria caused by Plasmodium falciparum results in serious illness and, if untreated, often leads to death. Although a number of candidate vaccines have progressed to clinical trials the efficacy rate of those vaccines was much lower than ideal. New methods for simultaneous presentation and immune stimulation of malarial antigens are needed in order to rapidly progress promising antigens into ef ...

In this Phase II research, Blacktoe Medical will design, manufacture and test a finger-worn ultrasound-imaging probe, optimized for Army vascular access requirements. The vascular finger probe will simplify use and reduce the time to learn complicated ultrasound guided procedures. By leveraging human hand-eye coordination and intuitive knowledge of finger position and orientation, the probe will a ...

The Phase II program concentrates on improving computational capabilities for analyzing hypersonic missile base flow configurations by utilizing state-of-the-art experimental data and complementary LES data to support development and validation of RANS turbulence models for propulsive base flows. Previously, CRAFT Tech has extended turbulence modeling capabilities for cold propulsive base flows ut ...

The Automated Algorithm Generator combines a distributed Framework infrastructure with a Library of diagnostic and prognostic algorithms to automate health reporting from widely dispersed Army combat and support vehicles. The Framework is a highly flexible and expandable skeleton for distribution of embedded algorithms, health assessment execution, report management, configuration management, heal ...

Multi-drug resistant (MDR) biofilms are one of the most difficult bacterial infections to treat. Current antibiotics are increasingly unable to cure these infections; underscoring the need to develop new antibiotics that operate through novel mechanisms which overcome the biofilm environment. PolyMedix has discovered a novel class of antibiotics, SMAMPS (small mimics of antimicrobial peptides), t ...

The goal of this effort is to create a hybrid software product that combines a full wave electromagnetic solver with a sophisticated circuit simulator creating an engineering tool that is capable of simulating the complete system of complex electronic devices. This tool will be powerful asset for a wide variety of government and industry users for applications that combine field and circuit intera ...

A Weigh-in-Motion (WIM) system is being developed that will deploy in or on roadways of all types and accurately measure and report weights of crossing vehicles, including total vehicle weight and individual axle and wheel weights. The innovation in the system is that it senses horizontal (lateral and longitudinal) forces at each wheel and uses those measurements to correct for vehicle weight shi ...

This proposal will lead to the development of a comprehensive aero-acoustic toolkit for predicting the acoustic signatures of tactical projectiles. Development will focus on identification of noise generation mechanisms and their spectral content, propagation of the noise through non-uniform media, accounting for effects of atmospheric attenuation and dispersion as well as prediction of the far-f ...

The program focus is a new semiconductor technology that enables direct device integrated passive persistent energy harvesting. The new semiconductor technology enables much of the (low/mid acoustic frequency) ambient shock and vibration energy to be efficiently converted into electrical energy. The design maximizes ability to harvest and store energy from such ambient mechanical excitation as to ...

In this SBIR Phase II project, first, we will develop a ready-to-use unconventional spatially coherent, wavelength selectable, high average power, broadband visible-IR source by leveraging the very promising and encouraging proof-of-concept results achieved at the Phase I stage. Such kind of source is realized by employing (1) a tunable, 3-dimensional, nanoengineered, high IR transmittance and hig ...