Award Data

This Phase II SBIR project will continue the development of an optical sorter that will be used to estimate drop sizes in sprays. The optical sorter will determine the size of drops in the 0.1 to 10 microns range. Drops in this size range are prevalent in the automobile industry, where the fuel injection pressures have increased tremendously over the past two decades. These newer injectors provide ...

TECHNICAL ABSTRACT: In this Phase II effort, PEMDAS Technologies and Innovations (PEMDAS), in collaboration with subcontractor Aerovel, Inc., proposes to fully develop a prototype Low-Altitude Maritime SurveySampling (LAMSS) System using the technologies identified and knowledge gained during our Phase I effort. The proposed innovation will deliver the necessary capabilities for electro-optical an ...

TECHNICAL ABSTRACT: During Phase I, Metron designed and implemented an efficient, scalable, end-to-end prototype system for collecting, storing, and viewing mariner weather observations: the Mariner Report App (MARApp). The MARApp Client is a mobile application that transforms smartphones and tablets at sea into forward geospatial/environmental sensors. It can take weather measurements from sensor ...

ABSTRACT Yellow fever virus (YFV) represents a mosquito-borne emerging/re-emerging human pathogen that causes 20- 50% mortality and is endemic in andgt;40 countries. The current live attenuated YFV vaccine was developed in 1936 and following the establishment of a virus seed lot system, it has not been modified or otherwise improved in over 50 years. According to the CDC, this vaccine causes 47 se ...

Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

IntroductionThe Glove Rehabilitation Application for Stroke PatientsGRASPFast Track SBIR program will promote recovery of hand function following stroke through an instrumented orthosis that enables functional practice of manual tasks in fun and engaging activities within a virtual environmentThe effort combines patented sensor glove technology developed under the NASA space suit program with a co ...

Project Summary The nematode worm Caenorhabditis elegans has proven valuable as a model for many high impact medical conditionsThe strength of Celegans derives from the extensive homologies between human and nematode genesand the many powerful tools available to manipulate genes in Celegansincluding expressing human genesResearchers utilizing medical models based on Celegans have converged on two ...

Project Summary Although potent antithrombotic agents are availableall of these drugs inadvertently target vital hemostatic molecular mechanismsresulting in dose limiting hemorrhagic toxicity that restrict their useDue to a lack of safe thromboprophylaxisthrombotic blood vessel occlusions continue to be extremely prevalentand result in a wide range of severe disease conditions that remain the lead ...

ABSTRACT Neurological and neurodegenerative disordersincluding Alzheimer s diseaseADParkinson s diseasePDHuntington s diseaseHDand amyotrophic lateral sclerosisALSare characterized by heterogeneous disease progressionAs a groupthese complex diseases are influenced by an interplay between several genetic and environmental factorsDrug development for these diseases could benefit from a framework tha ...

Project Summary Mobility limitations including gait and balance impairments are common in older adultsespecially those with neurological de citsGait and balance impairments are a major cause of falls and reduced quality of lifeAlthough laboratory studies show that biofeedback during exercise training can improve motor performancephysical therapists do not have access to an overground gait biofeedb ...