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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. System for Increasing Patient Access to Eye Exams for Diabetic Retinopathy

    SBC: AEON IMAGING LLC            Topic: NEI

    DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Fluorescence Anisotropy-based Macromolecule Crystallization Screening

    SBC: iXpressGenes, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Current practice is to set up trial crystallization screens and periodically review the results to see if a crystal or promising crystal-like precipitate has appeared a process that often takes weeks or months. Most outcomes are precipitated protein or clear drops, and the conditions that led to those results are removed from further consideration. We are deve ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Creating Resilient Structures with Polymer Coatings

    SBC: Optechnology, Inc.            Topic: 819S

    The first goal of our team is to design and develop highly ductile cement mortar composites using novel patent applied for technology which has been shown to produce materials with high energy absorption, decreased modulus, higher tensile strength, and greater toughness than standard or ultra high performance concretes or fibercements. These materials will be used to produce NEMA Class 5 flood res ...

    SBIR Phase II 2010 Department of Commerce
  4. A Novel Approach for Real-time Proteomics in Live Cells

    SBC: POWERHOUSE PROTEOMIC SYSTEMS LLC            Topic: NCRR

    DESCRIPTION (provided by applicant): The ultimate goal of this SBIR project is to develop a novel proteomic system that will enable the real- time expression profiling of proteins in live murine embryonic stem (mES) cells and in differentiated cells derived there from. The first step involves the establishment of a library of fluorescent trap mES cell lines, each of which will harbor a single fluo ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Kidney Multiphoton Analysis of Therapeutic Agents

    SBC: INPHOTON, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The rate of drug development is disappointingly slow, in part because of the failure of preclinical drug studies to elucidate the mechanisms of drug actions. INphoton has demonstrated that intravital microscopy can be used as a powerful tool in preclinical drug studies, providing the mechanistic insights typically associated with studies of cultured cells, but ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Separation Biosensor for Pharmacological Applications

    SBC: Bioanalytical Systems, Inc.            Topic: N/A

    The overall objective of this study is to develop a system that can be used to monitor pharmacokinepharmacological or neurochemical events in near real time. This will be accomplished by coupling micdirectly to capillary electrophoresis (CE). The system is much more versatile than conventional biossampling and analysis steps can be optimized separately. A system has been developed using CE with Ln ...

    SBIR Phase II 1997 Department of Health and Human Services
  8. Mitral Mechanical Heart Valve Dynamics and Cavitation

    SBC: CFD RESEARCH CORPORATION            Topic: N/A

    Occluder dynamics and valve hemodynamics in mechanical heart valves (MHV's) are strongly coupled. Wdevelop a numerical fluid-structure interaction model for predicting leaflet dynamics as a functionphysiologic flow rates in-tilting disk mitral MHV's. The Influence-Coefficient method, which we earlstructure interactions in natural aortic valves, will be adapted for simulating mitral MHV dynamics.di ...

    SBIR Phase II 1997 Department of Health and Human Services
  9. Rapid Scanning Near-Infrared/Infrared Spectrometer

    SBC: En'urga Inc.            Topic: N/A

    This project involves a feasibility study for a rapid scanning near-infrared/infrared spectrometer for transient, simultaneous measurements of CO2 and H20 concentrations, soot volume fractions and temperatures. Such measurements can lead to improved understanding of the structure of turbulent and laminar flames. A commercial instrument that can reliably provide simultaneous gas concentrtaion, so ...

    SBIR Phase II 1997 Department of Commerce
  10. N/A

    SBC: ENDOCYTE, INC.            Topic: N/A

    N/A

    SBIR Phase II 1997 Department of Health and Human Services
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