Award Data

DESCRIPTION (provided by applicant): In this Phase II SBIR project, Concordance Health Solutions (CHS) will continue development of the ScanCap System and test its effectiveness on adherence rates and hypertension patient outcomes The ScanCap System is anelectronic reminder cap that is seamlessly programmed at the pharmacy and incorporated into original packaging for prescription medications. The ...

DESCRIPTION (provided by applicant): An estimated 23.6 million people (7 percent of the population) in the United States have diabetes; 90 to 95 percent of all diagnosed cases are type 2 diabetes (CDC, 2007). Obesity and metabolic syndrome are the leadingcauses of type 2 diabetes. The search for new and more effective therapies to address the growing number of Americans with type 2 diabetes and re ...

DESCRIPTION: PROJECT SUMMARY/ABSTRACT. This Phase II SBIR project, Game FACTS (Fun, Adaptable-Content Trainer Suite): The Use of Microgames as a Supplemental Learning Tool for Worker Health and Safety Training builds upon the work of the previously fundedPhase I SBIR project Micro-games for WMD Training for Skilled Support Personnel. Phase I focused on the development of microgame (i.e., short-dur ...

DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

DESCRIPTION (provided by applicant): The ultimate goal of this SBIR project is to develop a novel proteomic system that will enable the real- time expression profiling of proteins in live murine embryonic stem (mES) cells and in differentiated cells derived there from. The first step involves the establishment of a library of fluorescent trap mES cell lines, each of which will harbor a single fluo ...

DESCRIPTION (provided by applicant): The rate of drug development is disappointingly slow, in part because of the failure of preclinical drug studies to elucidate the mechanisms of drug actions. INphoton has demonstrated that intravital microscopy can be used as a powerful tool in preclinical drug studies, providing the mechanistic insights typically associated with studies of cultured cells, but ...

The overall objective of this study is to develop a system that can be used to monitor pharmacokinepharmacological or neurochemical events in near real time. This will be accomplished by coupling micdirectly to capillary electrophoresis (CE). The system is much more versatile than conventional biossampling and analysis steps can be optimized separately. A system has been developed using CE with Ln ...

This project involves a feasibility study for a rapid scanning near-infrared/infrared spectrometer for transient, simultaneous measurements of CO2 and H20 concentrations, soot volume fractions and temperatures. Such measurements can lead to improved understanding of the structure of turbulent and laminar flames. A commercial instrument that can reliably provide simultaneous gas concentrtaion, so ...

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Lipoprotein(a) [Lp(a)] has been labelled the most atherogenic lipoprotein in man. Current laboratorLp(a) employ immuno-quantitation of its apolipoprotein [apo(a)]. Because these methods are hamperedto plasminogen, apo(a) isoform dependence, antibody heterogeneity, and lack of standardization, noneapproved. One third of Lp(a)'s mass is cholesterol, and only one tenth is apo(a). We will develop ola ...