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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. OPEN FILE FORMAT AND PUBLIC DOMAIN TOOLS FOR NEURAL DATA

    SBC: Bionic            Topic: N/A

    There are many data acquisition systems available for neuroscientists interested in multi-channel neurophysiology but all use proprietary, independently-developed file formats for the acquired data. This creates several problems including difficulties in sharing data between laboratories and poor interoperability between equipment, data processing tools and spike classification software from diffe ...

    SBIR Phase II 2002 Department of Health and Human Services
  2. PDA CAPTURE OF ELECTRONIC SOURCE DOCUMENTS

    SBC: COGNITECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2002 Department of Health and Human Services
  3. TRANSCUTANEOUS INFRARED TELEMETRY LINK

    SBC: CYBERKINETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The program will develop a close-coupled, transcutaneous telemetry system for exchanging electrical power and high bandwidth data across intact skin. Electrical power will be transmitted to the implant by RF inductive coupling and data will be received from the implant by a modulated, low-intensity infrared beam. The telemetry components produced by this prog ...

    SBIR Phase II 2002 Department of Health and Human Services
  4. HIGH-THROUGHPUT RF COILS FOR HIGH-FIELD MRI

    SBC: DOTY SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant):Improvements in signal to noise ratio (SNR) and ease of use of magnetic resonance imaging (MRI) RF coils are needed to improve image quality and patient throughput. The goal of this Phase II project is to continue the development of novel rf coil topologies and rf balancing circuits that have demonstrated substantially improved technical performance, reduced co ...

    SBIR Phase II 2002 Department of Health and Human Services
  5. PHOSPHOINOSITIDE 3-KINASE ASSAYS IN CANCER DIAGNOSIS

    SBC: ECHELON BIOSCIENCES, INC.            Topic: N/A

    Phosphoinositides are key lipid second messengers in cellular signaling. No approved diagnostics evaluate lipids as markers for cancer, but analysis of lipids in addition to protein and DNA may enhance overall accuracy of diagnosis and simultaneously suggest a molecular target for treatment. The tumor promoter phosphatidylinositol 3-kinase (PI3-K) regulates protein trafficking, proliferation and d ...

    SBIR Phase II 2002 Department of Health and Human Services
  6. REAL-TIME GENE QUANTIFICATION WITH INTERNAL STANDARDS

    SBC: IDAHO TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Real-time PCR has greatly improved the ease, accuracy and precision of quantitative PCR by allowing reaction kinetics to be observed, measured and recorded as PCR is occurring. We have successfully commercialized the LightCycler, a real-time PCR instrument that combines a rapid thermal cycler with a fluorimeter. We have developed s ...

    SBIR Phase II 2002 Department of Health and Human Services
  7. A NEW CLASS OF DRUG CARRIERS FOR TREATMENT OF MS

    SBC: KK Biomed Corporation            Topic: N/A

    DESCRIPTION (adapted from applicant's abstract): A patented, new class of drug carriers comprised of polymerized cyclodextrin (polyCD) will be synthesized and characterized for the treatment of MS. The carrier will provide a macromolecular delivery system through entrapment of the drug without conjugation. This can reduce side effects and increase bioav ...

    SBIR Phase II 2002 Department of Health and Human Services
  8. IMPROVED ALLOGRAFT HEART VALVE PRESERVATION

    SBC: ORGAN RECOVERY SYSTEMS, INC.            Topic: N/A

    Cryopreserved allogeneic human heart valves are presently the preferred aortic and pulmonary heart valve prostheses for pediatric patients, women of child-bearing age and non-drug compliant patients. Unfortunately, these valves often deteriorate in younger pediatric patients. The objective of this proposal is development of cryopreservation methods that cause less inter ...

    SBIR Phase II 2002 Department of Health and Human Services
  9. CRYOPRESERVATION OF ARTICULAR CARTILAGE BY VITRIFICATION

    SBC: ORGAN RECOVERY SYSTEMS, INC.            Topic: N/A

    Fresh osteochondral allografts have been proven clinically effective. However, the logistics of getting fresh, viable cartilage from donor to recipient requires the development of tissue banking methods. Conventional cryopreserved osteochondral grafts perform poorly in vivo and it is well established, in other tissue systems, that conventional cryopreservation often results in potentially damaging ...

    SBIR Phase II 2002 Department of Health and Human Services
  10. HIGHLY ORIENTED PEEK/PEEK COMPOSITES FOR DENTAL IMPLANT

    SBC: POLY-MED, INC.            Topic: N/A

    The Phase I study demonstrated the feasibility that highly oriented PEEK and carbon-fiber-reinforced PEEK (CFR-PEEK) could be engineered as surface phosphonylated dental implants and these implants could be microtextured to enhance osseointegration. In the Phase I study, surface-phosphonylated and microtextured rods composed of solid-state oriented PEEK and CRF-PEEK were implanted transcortically ...

    SBIR Phase II 2002 Department of Health and Human Services
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