Award Data

Corvid Technologies, LLC and Stevens Institute of Technology (Stevens) propose to utilize the results and lessons learned from the Phase I effort to develop and demonstrate a digital human body model capable of quantifying internal stresses and strains in the anatomy and joint loads due to externally applied forces from robotic manipulation. Similar to the approach in Phase I, the proposed approac ...

Hemorrhagic shock is responsible for over 35% of prehospital traumatic deaths and over 40% of all deaths within the first 24 hours following injury. Multiple intervention strategies are necessary for prolonged prehospital management and improved casualty survivability including improved blood products, hemostatics, damage control resuscitation, as well as therapeutic interventions targeting coagul ...

The purpose of this SBIR topics is to define, demonstrate, develop, and test an Intelligent Patient Simulation software architecture to be used for building intelligent patient simulators that provide realistic medical training experiences, by leveraging natural language processing and advanced Artificial Intelligence (AI) technologies.

Vadum and K9 Helm propose to combine Vadum canine Hearing Protection (HP) technologies (including both passive and active protection modes) with K9 Helm Military Working Dog (MWD) helmet technologies. The K9 Helm products provide several additional functions (beyond HP) including eye protection, muzzle functionality, and mounting points for other sensors. The combined functionality supports freque ...

The management of infection caused by multidrug-resistant (MDR) Pseudomonas aeruginosa is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. P. aeruginosa is one of the most common gram-negative bacteria implicated in nosocomial infection and the second most common pathogen implicated in ventilator-associated pneumonia (VAP). The excessive use of antib ...

Acute radiation syndrome (ARS) is a severe illness that occurs when a person is exposed to high levels of ionizing radiation, typically within a relatively short period. The hematopoietic system is most vulnerable for radiation exposure since mild symptoms may occur at the exposure dose of as low as 0.3 Gy, and severe ionizing radiation-induced hematopoietic failure usually results in lethal infec ...

Corvid Technologies, LLC and Illinois Institute of Technology (IIT) propose to build upon the experimental characterization and mathematical modeling techniques developed for cardiac tissue transition boundaries to improve the state of human brain tissues modeling. The approach will focus on the development of blended tissue models for brain tissue to improve the modeling accuracy for neurosurgica ...

No currently available burn product has shown efficacy in substantially decreasing wound healing time and preventing scar formation. The goals of this Phase II proposal are to expand on the results obtained in the Phase I study that showed that (1) halofuginone inhibited collagen-mediated contracture in dermal fibroblasts and (2) the presence of the keratin in the KeraStat burn product results in ...

The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

Burn injuries to theface present a number of functional and psychological challenges that arisefrom scarring and contracture. Thus, amajor goal of burn and trauma surgeons is to prevent scarring and improvegraftingtechnologies that are used on thecomplextopography of the face. The proposed project builds on previous PhaseII SBIR workthat demonstrated thefeasibility of using a keratin-collagen matr ...