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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Device to Quantify Sweat of Single Sweat Glands to Diagnose Neuropathy

    SBC: Neuro Devices, Inc.            Topic: 107

    DESCRIPTION provided by applicant We devised a new generation highly sensitivity method to diagnosis peripheral neuropathy early when the probability for reversal is greatest Cancer chemotherapy and diabetes are the most common causes of neuropathy in the USA Both cause decreased sweating abnormal circulation peripheral numbness pain and weakness If diagnosed early both are potentially ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A fluorescent reporter detecting precise homologous recombination transgenesis activity

    SBC: KDT, LLC            Topic: NICHD

    The broad long term objective and specific aims of the fast track SBIR research are to create a reagent RecombiRED for use in microinjection of embryos for identifying a subset of embryos as recombination competent injections The ability to quickly identify genome editing events in an embryo allows researcher to quickly make precision animal models of human disease states Precise animal m ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A Low Power Wireless Pulse Oximeter Sensor for Unobtrusive Wearable Applications

    SBC: KORONIS BIOMEDICAL TECHNOLOGIES CORP.            Topic: N

    DESCRIPTION provided by applicant Koronis Biomedical Technology Corporation KBT proposes to develop and evaluate a miniature ultra low power pulse oximeter for long term wearable monitoring There continues to be a clinical need for an unobtrusive pulse oximeter sensor that is small and can be worn comfortably for extended periods of time without battery change or recharge KBT will use eye s ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Anti-Inflammatory Glycosaminoglycan Ethers for Treatment of Periodontitis

    SBC: GLYCOMIRA, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Chronic gingival inflammation of the soft tissue surrounding the tooth afflicts over half of all American adults In the most severely affected progression of this inflammatory process to the deeper periodontal ligaments and alveolar bone results in tooth loss from loss of mandibular anchorage Gingivitis and periodontitis are initiated by chronic infection o ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Automated Problem and Allergy Lists Enrichment Based on High Accuracy Information Extraction from the Electronic Health Record

    SBC: Clinacuity, Inc            Topic: NCI

    DESCRIPTION provided by applicant Medical errors are recognized as the cause of numerous deaths and even if some are difficult to avoid many are preventable Computerized physician order entry systems with decision support have been proposed to reduce this risk of medication errors but these systems rely on structured and coded information in the electronic health record EHR Unfortunately ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: TheraTarget, Inc.            Topic: NCI

    DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Blocking a novel cytokine signaling pathway for the treatment of rheumatoid arthr

    SBC: NAVIGEN, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant In spite of remarkable progress in management of rheumatoid arthritis RA a devastating autoimmune disease that affects million Americans causing chronic inflammation of joints and surrounding tissues the gap of unmet needs in this therapeutic field remains wide open First of all almost of the patients do not respond adequately to the most advanced ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Child Safety Seat with Advanced Harness System

    SBC: Minnesota HealthSolutions Corporation            Topic: NICHD

    Project Summary Abstract Minnesota HealthSolutions MHS proposes to develop an advanced harness system for motor vehicle child safety seats Motor vehicle crashes are the leading cause of death for American children A total of children aged years or younger died as a result of unintentional motor vehicle traffic crashes from and hundreds of thousands more were injured When used ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Compact Swept Near Infrared Light Source for Broadband Diffuse Optical Spectroscopic Imaging of Breast Malignancies

    SBC: Vixar Inc.            Topic: 102

    DESCRIPTION provided by applicant This project will develop swept wavelength laser light sources at several frequencies in the near infrared NIR While applicable to numerous applications the goal is to use these laser sources as an enabling technology for Diffuse Optical Spectroscopic Imaging DOSI a technique which allows noninvasive characterization of human tissue and can monitor and p ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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