Award Data

DESCRIPTION (provided by applicant): The central goal of this research is to develop a new drug to prevent spinal cord reperfusion injury secondary to aortic clamping that occurs frequently during thoracic surgery. Irreversible spinal cord injury resulting in paraplegia or paraparesis is the single most devastating complication of surgery on the thoracic and thor ...

epsis syndrome is the 11th leading cause of death in the United States ( about 900,000 new cases per year) with a mortality of about 35 percent. The need for adjunctive therapies is urgent. In Phase I of this SBIR award we documented the anti-inflammatory effects of adenosine A2A receptor (A2AAR) agonists on isolated immune cells and have observed ramatically improved survival in mouse models of I ...

DESCRIPTION provided by applicant Introduction The Blink based Communication BLINC System will allow any patient who retains oculomotor control to reliably signal for assistance and communicate basic requests to a caregiver It uses infrared IR cameras and illuminators to continuously monitor a patient in bed and to detect blink signals even in a dark room It is specifically designed so ...

DESCRIPTION (provided by applicant): The major objective of the proposed project is to develop methodology that will allow fast and efficient detection of infectious prion proteins prior to the onset of clinical symptoms. This includes the detection of infectious prions in mortal products, early ante-mortem diagnostic of the prion diseases, and developing experimental approaches allowing deline ...

SCI incidence ranges from 250k-500k globally/year, with rt7M people impacted. Currently rt300k U.S. individuals live with SCI. SCI results in life-altering consequences in terms of morbidity, mortality, functional status, employment, and quality of life. For quadriplegics with cervical injuries, even basic ADLs are severely compromised. Individuals learn assistive strategies for ADLs such as eatin ...

DESCRIPTION (provided by applicant): Many high schools use a graphing scientific calculator to assist students in math and science courses. These calculators have a built-in screen and displays graphs and perform scientific functions. These calculators are used widely in higher math (Algebra I and beyond) and science courses. They are a valuable tool for high school teachers and students. Unfor ...

DESCRIPTION (provided by applicant): People using wheelchairs are more active than ever before. Their wheelchair is a mobile station, a base from which they work, play and interact. Access from their wheelchair is essential, yet people are constrained by limitations imposed by existing mounts. Accessible mounting technology increases the independence and mobility of people with disabilities, resu ...

DESCRIPTION (provided by applicant): The AccuNurse System has been successfully developed in Phase I to provide an easy-to-use "mentor" and communications tool for CNAs and nurses in skilled nursing units. Wireless and advanced speech technologies are merged into a conversational system that provides: individualized resident information, paperless documentation at the point of care, and many other ...

Abstract In this Phase II SBIR project ASTER Labs will enhance a wireless WiFi based insole that was designed and successfully tested and evaluated during a Phase I trial with elderly persons with dementia and their caregiversand then investigate its efficacy in reducing caregiver activity and burdenand improving caregiver quality of lifeAn estimatedmillion Americans had Alzheimer s disease inand ...

DESCRIPTION (provided by applicant): Koronis Biomedical Technologies Corporation (KBT) proposes the development of a chronic disease management solution. According to the NIH, chronic diseases in 2005 will account for 75% of U.S. healthcare costs. The proposed solution will serve the large population of patients suffering from one or more of four chronic illnesses: diabetes, congestive heart failu ...