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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Computer Model of Renal Physiology for use as a FDA Medical Device Development Tool

    SBC: HC SIMULATION LLC            Topic: FDA

    The purpose of this proposal is to develop a validated physiological model of the human physiologyespecially the cardio renal axisfor submission to the FDA Medical Device Development Tool pilot programThe model will be used to aid in the development and regulation of medical devices designed to treat hypertensionExamples include devices for renal nerve ablationelectrical stimulation of the carotid ...

    SBIR Phase II 2018 Department of Health and Human ServicesFood and Drug Administration
  2. Advanced Fast Shutter for Debris Mitigation

    SBC: HYPERION TECHNOLOGY GROUP INC            Topic: DTRA143007

    In an effort to development more robust optical system coatings DTRA, in collaboration with Sandia National Labs, is working to characterize the degradation of optical materials for space systems when exposed to high intensely EUV/ cold x-rays. The experiments utilizes the Double Eagle z-pinch facility which generates high current, high voltage arc pinch plasma to produce an intense EUV and cold x ...

    SBIR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  3. Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): Poison ivy/oak contact dermatitis is the most prevalent skin allergy in the United States, affecting gt50% of the adult population. The condition is the major cause of occupational hazard among outdoor workers in forestry, agriculture and firefighting, resulting in significant medical expenses and workers disability. Attempts have been made to provide prophyla ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. DEVELOPMENT OF A NEW DOSAGE FORM FOR LONG-TERM STUDIES OF ^9-THC

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    STUDIES IN THIS PROPOSAL WILL BE AIMED AT THE PREPARATION OFA SUPPOSITORY FORMULATION OF A PRO-DRUG OF DELTA-9-TETRA- HYDROCANNABINOL (^9-THC) AND STUDY THE BIOAVAILABILITY OF THC FROM THIS FORMULATION AS COMPARED TO I.V. ADMINISTRATIONOF BOTH THC AND ITS PRODRUG. BIOAVAILABILITY STUDIES WILL BE CONDUCTED IN MONKEYS, AND BLOOD SAMPLES WILL BE COLLECTEDAT 0, 15, 30, 60, 90, 120, 180, 240, AND 480 M ...

    SBIR Phase II 1988 Department of Health and Human Services
  5. FLUORESCENCE SYSTEM FOR SENSING BIOSPECIFIC INTERACTIONS

    SBC: TIRF Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): An innovative fluorescence system for sensing biomolecular interactions was developed in Phase I that is based on total internal reflection fluorescence (TIRF). The main advantages of this system are integrated microfluidics and a design that allows rapid replacement of TIRF sensor chip. The feasibility of building a highly sensitive and versatile TIRF biosenso ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  6. IDENTIFY/ANALYZE THC AND COCAINE METABOLITES IN MECONIUM

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    N/A

    SBIR Phase II 1997 Department of Health and Human Services
  7. Microscopic Traffic Flow Simulation Models- An Open Source Approach

    SBC: NEW GLOBAL SYSTEMS FOR INTELLIGENT TRANSPORTATION MANAGEMENT CORPORATION            Topic: 081FH5

    PHASE II TECHNICAL OBJECTIVE The major objective of this Phase II proposal is to establish open source traffic simulation model and software, and to develop application programming interfaces to accommodate future traffic research needs. Objectives will be accomplished by building and demonstrating FOMM, an open source traffic simulation model and software. Furthermore, to accommodate future resea ...

    SBIR Phase II 2011 Department of Transportation
  8. N/A

    SBC: ElSohly Laboratories, Incorporated            Topic: N/A

    N/A

    SBIR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Munition Technologies to Attack and Defeat Weapons of Mass Destruction (WMD)

    SBC: HYPERION TECHNOLOGY GROUP INC            Topic: DTRA143004

    Traditional weapon systems often fail to meet the requirements of close combat typical of the previously discussed engagement, where insurgents often blend in or store weapon amongst friendly or non-combatant forces, to shield them from precision strike munitions of a technologically superior force. This type of warfare has led to an increased focus on the use of less-lethal weapons, to reduce let ...

    SBIR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  10. Renal Therapeutic Angiogenesis Using the Novel Biologic ELP-VEGF

    SBC: LEFLORE TECHNOLOGIES LLC            Topic: 400

    Abstract.Chronic kidney disease (CKD) is a progressive disorder affecting almost 14% of the general population, and this disease has shown a relentless growth over the past 2 decades. Patients with CKD have higher rates of hospitalization, greater mortality, shorter life expectancy, and their healthcare costs are up to 5 times more expensive than non-CKD patients. Thus, treatments to slow, halt, o ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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