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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. High Sensitivity, Low Complexity, Multiplexed Diagnostic Devices

    SBC: Paratus Diagnostics            Topic: CBD152005

    Our goal is to provide the Department of Defense with a reliable, point-of-need diagnostic device that is field-deployable, appropriatelysensitive, and can be easily adapted for detection of a variety of biological targets that are of interest to the defense community. Phase I of thisproject was for the initial demonstration and development of our low-cost personal diagnostic platform (referred to ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Hermetic Seals for Chemical/Biological Protective Garments

    SBC: CREARE LLC            Topic: CBD13109

    Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic airgaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare is developinghermetic garment closure systems that seal macroscopic and microscopic gaps at interfaces and closures and provide high c ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments

    SBC: nanoGriptech, Inc.            Topic: CBD13109

    In previous SBIR Phase I/II work, nanoGriptech developed novel microfiber-based hybrid closure systems inspired by the foot-hairs on geckolizards which demonstrated the strength of military grade hook and loop systems with hermetically-sealable properties for improvedchem/bio protection. In this Sequential SBIR Phase II project, nanoGriptech will develop methods to integrate these innovative faste ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Medical Countermeasure Development for Viral Induced Encephalitis Using Single DomainAntibodies

    SBC: Abzyme Therapeutics, LLC            Topic: CBD161004

    Alphaviruses, infection with which may cause encephalitis and death, are recognized as potential biological warfare agents. There are noapproved medical countermeasures against Alphaviruses. In Phase I, using Abzymes proprietary in vivo Self-Diversifying Camelid SingleDomain Antibody Library (SDALib) platform, broadly reactive single domain camelid VHH antibodies against equine encephalitis viral ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  6. High-affinity monoclonal antibodies that target Burkholderia Polysaccharide

    SBC: DxDiscovery Incorporated            Topic: CBD14105

    The purpose of this contract is to develop high affinity antibodies that are specific to Burkholderia surface expressed polysaccharides. Thesemonoclonal antibodies (mAbs) can then be used to develop diagnostics and therapeutics for melioidosis and glanders; two infectious diseasescaused by the Tier 1 biothreats Burkholderia pseudomallei and mallei, respectively. The SBIR funded work to date develo ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  7. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Zymeron Corporation            Topic: CBD161003

    The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  8. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Nano Terra, Inc.            Topic: CBD161003

    Chemical warfare agents (CWAs), such as nerve agents and mustard agents, pose serious threats to our warfighters and civilians. Current formulations of dermal medical countermeasures to CWAs can be absorbed through the skin causing systemic toxicities to the patients. These formulations are limited by the FDA for use only in small area of intact skin. This severely restricts the usefulness of thes ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  9. Signal Processing for Layered Sensing

    SBC: Vadum, Inc.            Topic: CBD152006

    Vadum will develop Chemical, Heterogeneous sensor fusion Incident awareness Module (CHIME)asoftware module that will ingest data from a large number of asynchronous, heterogeneous and multi-tiered sensors to automate the process of estimating the source attributes of a chemical or biological release. CHIME generates estimates from a continuous stream of raw sensor data with successive estimates al ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  10. Adaptive Lens for Ocular Correction in Respiratory Protection Systems

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD152001

    To address the CBDs need for adjustable optical correction technology for respiratory protective systems, Physical Optics Corporation (POC)proposes to continue the development of a new low-cost Adaptive Lens for Ocular Correction (ALOC). The ALOC is formed by thin-filmmicroarrays of wavefront correctors (MWCs), which are conformably laminated onto the facemask visor and controlled by a miniature d ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense

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