Award Data

CMC Pharma is proposing this Phase II SBIR to continue the development and testing of a multi-dose vial of a scopolamine hydrobromide trihydrate (Scop-HBT) ready-to-use intramuscular solution formulation. The Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Medical (JPM CBRN Medical) is developing Scop-HBT under the Improved Nerve Agent Treatment System - Centrally Acting ...

SRICO proposes state-of-the-art metamaterial based sensing technology to coherent hyperspectral imaging in the W-band portion of the MMW spectrum. The metamaterial absorber pixel design provides spectrally tailored and phase sensitive vector mode sensing capability critical for W-band imaging. The proposed imaging array features spectrally tailored and deeply sub-wavelength size metamaterial pixel ...

CMC Pharma (Solon, OH) proposes continued development of a stable, fixed-dose combination drug product of atropine and scopolamine as a countermeasure to chemical warfare nerve agents (NA). The combination drug product is expected to exploit complementary pharmacological profiles for optimal anticholinergic activity within the peripheral and central nervous systems. Targeting both the peripheral a ...

CMC Pharmaceuticals, Inc. (Cleveland, OH) has proposed developing a stable, combination product of two small molecule drug candidates as a countermeasure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. I ...

Alphaviruses pose significant risks to warfighters where encephalitic virus infection can lead to death. There is no effective treatment foralphavirus induced encephalitis and countermeasures are of high importance. Single domain antibodies (sdAb) are low molecular weightengineered antibody fragments composed of a single heavy-chain variable domain which have proven easier to manipulate and re-eng ...

An innovative phase-cancelled radio frequency/microwave graphene-based impedance chemical gas sensor has been demonstrated in Phase I with the record high sub-ppb sensitivity of NH3 and DMMP in air. Our sensor shows excellent selectivity for sensing NH3 and DMMP in a complex environment, and is capable of in-situ multiplexed sensing. In Phase II, the sensor will be fully integrated on a 3 glass wa ...

Under the current SBIR solicitation, the DoD is interested in the development and demonstration of aircraft decontamination processes that are capable of completely detoxifying both chemical and biological warfare agents without increasing susceptibility to corrosion or adversely affecting the performance, properties, or appearance of aircraft materials. Decontamination processes may include indi ...

The United States Government has spent hundreds of millions of dollars developing decontamination capabilities to protect our military personnel and equipment from chemical warfare agents. With over 20 countries now having the capability to manufacture and use biological warfare agents, and the reality of the events involving the use of Anthrax on US soil after September 11, 2001, decontamination ...