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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs

    SBC: RADIOMEDIX, INC.            Topic: NCI

    A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 343- Cognitive Assessment and Monitoring Platform For Integrative Research (CAMPFIRE II)

    SBC: Charles River Analytics, Inc.            Topic: NCI

    Cancer survivors commonly report cognitive impairments following chemotherapy. With a growing number of cancer survivors comes an increased urgency to better understand the precise etiology and prevalence of cognitive changes associated with cancer and cancer treatment. This pursuit is impeded by a lack of assessment tools that can accurately detect the full scope of cognitive deficits. To address ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 345: RadTox- Measuring Radiation Toxicity using Circulating DNA

    SBC: DiaCarta, Inc.            Topic: NCI

    The QuantiDNA RadTox System is a unique, patented technology that measures tissue damage shortly following injury using cell-free DNA from a drop of blood. Premised on murine and primate studies showing circulating DNA is logarithmically increased with whole-body radiation dose, RadTox has the potential to overcome many of the species-specific challenges faced by biomarker panels. The phase I SBIR ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 352: Cell-Based Models for Prostate Cancer Health Disparity Research- Moonshot

    SBC: Shuttle Pharmaceuticals, LLC            Topic: NCI

    Prostate cancer health disparities studies have shown that African-American (AA) men are at higher risk for developing prostate cancer, as well as at higher risk of cancer specific death rates, as compared to Caucasian American (CA) men. Causes of disparities have been attributed to socioeconomic differences, environmental exposures and biological factors; however, the lack of relevant in vitro an ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Topic 349: Quantum Dot FRET Immunoassay to Quantify Intramolecular Epitopes of Analytes in Tissue Sections

    SBC: Ocean Nano Tech LLC            Topic: NCI

    This proposal is to develop a novel slide based proximity assay platform to quantify protein phosphorylation on tissues. The novelty of this assay platform is derived from the use of the quantum dot with two emission peaks for fluorescence resonance energy transfer (FRET): one emission as internal standard and the other as FRET donor. Change of ratio of the two emission intensity during the FRET c ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Topic 343- MindCap: Monitoring for Cognitive Impairment and Dyfunction in Cancer Patients

    SBC: Intelligent Automation, Inc.            Topic: NCI

    Persistent cognitive impairment is a frequent complaint of cancer patients undergoing chemotherapy. The current tests used to assess cognitive function are not sensitive enough to capture the degree of decline associated with cancer-related cognitive impairment (CRCI). In addition, they require professional administration and are subject to practice effects so they cannot practically be used for t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Analytical Tools and Approaches for (Multidimensional) Scholarly Research Assessment and Decision Support in the Biomedical Enterprise

    SBC: NET ESOLUTIONS CORPORATION            Topic: NIDA

    NIHthrough NIDAseeks advanced tools that could be broadly used by the life science community and generate results that would be understood by non scientists as well as professional evaluatorsIn Phase Ithe Contractor completed initial development of ERNIEan accessible big data platform integrating multiple data sources and associated methods for quantitative description of research that would facil ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Creation of an Accurate Model of the Topical Structure of PubMed and associated indicators

    SBC: SCITECH STRATEGIES, INC            Topic: NIDA

    NIH through NIDA seeks development of an advanced and sophisticated analytical tool and approaches to enhance the professional evaluation and decision support in life sciences management and administrationIn this Phase II project the Contractor will continue to develop indicators of impactful science and of how virtuous the research ise gtransparencyreproducibility and potential for translation ap ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A MULTIPLEXED REMOTE SYSTEM FOR FILOVIRUS DISEASE SURVEILLANCE

    SBC: Cellmic, LLC            Topic: NIAID

    Proposes an advanced Ebola and Marburg disease telemonitoring and assessment platform that will enable the digital modernization of point of care diagnosticsdisease surveillanceand healthcare screening by minimally trained personnel at the point of careOffering a complete diagnostics solutionthe platform includes a microfluidics assay for the detection of infections caused by Ebola and Marburg fil ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health

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