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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Software to Enrich the Noun Lexicons and Lexical Learning of Children with Autism

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The objective of this project is to develop and field-test prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be 3-8 year old children with Autism Spectrum Disorders (ASD), as well as a broad range of other children with languag ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. System for multidimensional analysis of growth and migration of neurons and neuro

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): This project aims at developing the Orion microscope system, a highly innovative combined software/hardware product, which will facilitate automated investigations of dynamics of migration of neuronal precursors and neurite outgrowth in vitro using time-lapse video-microscopy (TLVM). To achieve this goal, the Orion microscope system will combine novel software ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Development of the Pain Self-Management Program

    SBC: CONSULTANTS IN BEHAVIORAL RESEARCH            Topic: N/A

    DESCRIPTION (provided by applicant): Pain accounts for almost 80% of all of the office visits to physicians each year (National Center for Health Statistics, 1986; Stucky, Gold, & Zhang, 2001; Winterowd, Beck, & Greuner, 2003) and is a major source of disability, accounting for upwards of 700 million lost work days and $100 billion in health care costs per year (Report of the Commission on Evaluat ...

    SBIR Phase II 2007 Department of Health and Human Services
  6. High Precision Bioassay Using Robotics and Statistics

    SBC: LANSKY CONSULTING, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Cell culture bioassays are often laborious and imprecise even after substantial development efforts. These bioassays are used broadly in the biotechnology industry to measure protein or vaccine products in development and for lot release. Imprecise assays and slow assay development contribute to slow product development. Common practice in cell culture ...

    SBIR Phase II 2007 Department of Health and Human Services
  7. 3D Virtual Slide System for Creation and Analysis of Focusable Digital Slides

    SBC: MICROBRIGHTFIELD, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Rigorous quantification methods of histological specimens have become a keystone in modern neuroscience such as investigations of neurogenesis, stem cell research, neurotransplantation, neurotoxicology, and the pathogenesis of neurodegenerative and neuropsychiatric diseases. Methods in current practice are not conducive to high-throughput studies because they a ...

    SBIR Phase II 2007 Department of Health and Human Services
  8. Integrated Teleconferencing Unit For Home-Based Interactive Exercise For Elders

    SBC: MICRODESIGN CONSULTING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Supervised group exercise has been shown to be an effective component for improving balance and preventing falls among elders who have suffered falls or exhibit a fear of falling due to frailty. In a Phase I SBIR study, we developed a model for conducting group exercise programs for elders in their homes via video- conferencing, called tele-based group exercise ...

    SBIR Phase II 2007 Department of Health and Human Services
  9. Handwriting Teaching Tool

    SBC: NEUROSCRIPT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a system both for training efficient handwriting in school children and for scientific testing of hypotheses on handwriting education. Handwriting is the only and most widely learned fine motor skill. The US school system spends $200M per year (our estimate) on handwriting instruction materials. Teachers receive only limited training to teach ha ...

    SBIR Phase II 2007 Department of Health and Human Services
  10. Quality Control Tool for Newborn Screening Blood Samples

    SBC: WESTERN RESEARCH COMPANY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Essentially all newborns in the United States (about 4 million per year) and at least 30 other countries have blood samples obtained on filter paper cards for the purpose of screening for a number of metabolic and genetic diseases. To prevent morbidity, such as brain damage, from metabolic diseases such as phenylketonuria or congenital hypothyroidism, it is cri ...

    SBIR Phase II 2007 Department of Health and Human Services

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