Award Data

a. Paragon Space Development Corporation¿ (Paragon) proposes to continue our investigation into the use of microporous-ionomer membrane technology to improve the robustness and effectiveness and simplify water recovery processes for space applications. Improved robustness and effectiveness will be evident through (1) reduced loading onthe downstream post processor due to the ionomer¿s unique pr ...

There are a number of critical telemetry measurements to be monitored under continuous field operation, including temperature data across the reactor chamber and the nozzle, pressure data, neutron flux density and flow rate of the propellant. Real-time monitoring of this data in nuclear thermal engines would greatly improve operational safety and performance, reduce operational costs, and signific ...

Future NASA Space Science Missions will incorporate detectors, sensors, shields, and telescopes that must be cooled to cryogenic temperatures. An enabling technology for these missions is advanced cryocoolers that can provide continuous and distributed cooling with minimal input power. On this program, Creare proposes to develop and demonstrate an innovative cryocooler that produces refrigeratio ...

This proposal is responsive to NASA SBIR Topic X10.01, specifically, the need for efficient small- to medium-scale hydrogen liquefaction technologies, including domestically produced wet cryogenic turboexpanders. Future NASA missions will require hydrogen liquefaction systems for spaceport, planetary, and lunar surface operations. A critical part of these systems is the cryogenic expansion turbi ...

Frequency-locked single-frequency 2 micron fiber laser is proposed to be used for airborne/spaceborne coherent lidar measurements, i.e., Active Sensing of CO2 Emissions over Nights, Days, and Seasons. The laser is based on our proprietary fiber technology and extensive experience in fiber laser development, which features a compact, highly stable, frequency-stabilized light source. Advanced freque ...

DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

DESCRIPTION (provided by applicant): There is currently no effective treatment for recurrent small-cell lung cancer (rSCLC). The objective of this project is to utilize a monoclonal antibody, Abner, to develop new, rational, and successful treatment of rSCLC. The hypothesis being tested is that an abnormal vasopressin type 2 receptor (AbnV2R) present on these tumors will provide a sensitive, tumor ...

DESCRIPTION (provided by applicant): The objective of this project is to develop and field-test prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be 3-8 year old children with Autism Spectrum Disorders (ASD), as well as a broad range of other children with languag ...

DESCRIPTION (provided by applicant): There is an urgent need for speech generating devices (SGDs) designed for young children with complex communication needs. Available SGDs are difficult for children to use and time consuming for adults to program. Without appropriate SGDs, children miss valuable opportunities to communicate and develop language skills during their early years, when they are pr ...