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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Client-Centered Calibration of the NOAA Climate Forecast System

    SBC: PRESCIENT WEATHER LTD            Topic: 821C

    Prescient Weather process five integrated Phase II tasks to increase the value of the NOAA Climate Forecast System and to assist the private sector in managing weather and climate risk and opportunity: The Phase II tasks are: (1) Develop an optimal WCS seasonal multi-model ensemble by calibrating and combining the NWS CFSv2, the ECMWF SFSv4, and the new National Multi-Model Ensemble (NMME) to cre ...

    SBIR Phase II 2012 Department of Commerce
  2. Individualized Fatigue Management Program Technology for Trucking Operations

    SBC: PULSAR INFORMATICS, INC.            Topic: 091FM1

    Individual differences in vulnerability to sleep loss and fatigue from extended work hours and night work are a substantial problem in transportation policy making, work schedule development, fatigue risk management strategies, and prediction of performance impairment in real-world operations (Van Dongen et al. 2003; Mollicone et al. 2010). Our group was the first to document the considerable magn ...

    SBIR Phase II 2012 Department of Transportation
  3. Urban Forestry Modeling and Prioritization Tools

    SBC: Azavea Inc.            Topic: 81

    The Urban Forestry Modeling and Prioritization Tools project addresses the research and tasks necessary for creating cost effective, web-based software that assists urban foresters with strategically selecting planting locations in order to maximize impact on both the environment and local communities. Studies by the US Forest Service and other groups demonstrate the many environmental, health, ae ...

    SBIR Phase II 2012 Department of Agriculture
  4. Artificial Intelligence Software to Tutor Literary Braille to the Blind and Visually Impaired

    SBC: Quantum Simulations, Inc.            Topic: N/A

    Purpose: Braille is the primary medium of written communication for persons who are blind. Prior research shows that Braille literacy strongly correlates with stronger reading habits and the pursuit of higher education, whereas Braille illiteracy negatively impacts students' academic performance and ability to navigate the everyday world. A recent report found that there has been a dramatic declin ...

    SBIR Phase II 2012 Department of Education
  5. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. RAIL reduces variability and concentration of stress hormones in blood sampling

    SBC: ACTUATED MEDICAL, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): In this Phase II SBIR, Actuated Medical, Inc. (f/k/a Piezo Resonance Innovations, Inc) will complete the development of the Resonance Assisted Insertion Lancet (RAIL ) System to reduce animal pain and stress response during laboratory animal blood sampling. Public Health Problem: Understanding the physiological and biological mechanisms of aging is the focus o ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Defining T cell epitopes in Dengue virus infection

    SBC: IMMUNOTOPE, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): There is a well-recognized need to develop vaccines that stimulates humoral immunity as well as a potent T cell immunity in order to achieve protection from infection with pathogens. Although numerous investigations arefocused on developing vaccines that induce protective humoral responses, only a few studies are aimed towards developing specific T cell immunit ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Portable electronically controlled transdermal patch for enfuvirtide delivery

    SBC: ACTUATED MEDICAL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): In this Phase II NIH SBIR, Piezo Resonance Innovations will further optimize and test the Portable Transdermal Patch (PTP) - a needle-free platform delivery technology for drugs and vaccines that are currently deliveredsubcutaneously. The portable, 200gm (7oz) electronically-controlled transdermal patch for Enfuvirtide delivery employs a patented transducer tec ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Development of Small Antimicrobial Peptide Mimics as Drug-Resistant and Susceptib

    SBC: PolyMedix, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Malaria is a global disease causing gt 500 million clinical cases and gt 1 million deaths each year. Moreover, drug resistant Plasmodium falciparum has become a major problem. Therefore, it is crucial to discover new classes of drugs for anti-malarial drug design to combat resistant parasites. We propose that antimicrobial peptides (AMPs) may provide the basis ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human Services

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