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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Continuing Development of PPCM Vaginal Contraceptive Microbicide

    SBC: YASO THERAPEUTICS INCORPORATED            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to continue development of a novel, dual indication vaginal contraceptive anti-herpes microbicide product containing PPCM. We will conduct all tasks required to generate the Pharmacology/Toxicology and Chemistry Manufacturing and Controls (CMC) information required for IND submission, and outline the early clinical study designs with ...

    SBIR Phase II 2013 Department of Health and Human Services
  2. HazReady-Online- Device Agnostic- Multi-player Group Simulation Phase II

    SBC: Inxsol LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Project Summary inXsol proposes to design and demonstrate a web-based, multiplayer small group simulation to support instructor led HazMat worker health and safety training. This product is called HazReady. The use of distributed, low-cost simulation will allow individuals to attain a level of experience in the probable roles at typical incidents and work sites ...

    SBIR Phase II 2013 Department of Health and Human Services
  3. A pocket-sized device for personal exposure level assessment

    SBC: TF SENSORS, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): A pocket-sized device for personal exposure level assessment Abstract Detecting environmental toxicants is critical for better understanding of the relationship between chemical exposures and many diseases, and for more effective prevention of the related diseases. Due to large variations in the individuals' genetic susceptibility and environmental exposu ...

    SBIR Phase II 2013 Department of Health and Human Services
  4. Nuclease Probe Mediated Sequencing

    SBC: HIGH THROUGHPUT GENOMICS, INC.            Topic: NHGRI

    This Phase II proposal will complete the development of an innovative sequencing platform (NPSeq) based on feasibility demonstrated in Phase I. This platform uses a nuclease protection assay combined with universal PCR to produce targeted sequencing libraries. The lysis-only protocol means there is no need to extract RNA or DNA or to reverse transcribe RNA. Consequently, sequencing from fixed tiss ...

    SBIR Phase II 2013 Department of Health and Human Services
  5. The Transfusion Chip: Phase II Technology Validation

    SBC: GENOMICS USA, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Blood-Typing is the progenitor of the entire field of personalized medicine. In the recently awarded 6-month Phase I, we proposed to take the first step in the development of an extremely-low-cost microarray test, TheTransfusion-Chip (T-Chip) which convert the historical practice of Blood-Typing by serology into a simple inexpensive DNA test. Here, in this fo ...

    SBIR Phase II 2013 Department of Health and Human Services
  6. Automated 3D quantitative analysis of dendritic spines imaged with light microsco

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION provided by applicant In this Lab to Marketplace proposal we aim to develop the MBF SpineStudio software incorporating the innovative laboratory based NeuronStudio software created at the Mount Sinai School of Medicine Our SpineStudio software will enable automated detection reconstruction and morphological classification of the structural analysis of dendritic spines By creating this ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Subsurface Communications System for Robotics

    SBC: Sandia Research Corporation            Topic: DHS002

    Underground cross-border tunnels of all sizes and shapes are an increasingly important threat to our National security. Finding cross-border tunnels is a challenging task and once found, an additional challenge is secure and map the entire underground tunnel. Manned entry into these dangerous underground environments is a risky endeavor. The use of robotics offers a great improvement over human en ...

    SBIR Phase II 2013 Department of Homeland Security
  8. Model Center-Integrated Reduced Order Multi-fidelity Optimization Scheme for NASA MDAO Framework

    SBC: Zona Technology, Inc            Topic: A208

    During Phase I of this effort, ZONA Technology, Inc. significantly improved the medium fidelity design and analysis capability of NASA's MDAO architecture by successfully adding ZONA CAE tools such as ZAERO, ZEUS, ASTROS and ZMORPH synergistically integrated within a ModelCenter MDAO framework. In Phase II of this effort, ZONA aims to improve all the three tiers of NASA's MDAO architectu ...

    SBIR Phase II 2013 National Aeronautics and Space Administration
  9. 1.55 Micron High Peak Power Fiber Amplifier

    SBC: AdValue Photonics Inc            Topic: S101

    In this proposal, we propose to demonstrate and build a 1.55 micron single frequency high energy and high peak power fiber amplifier by developing an innovative Er-doped gain fiber with large core diameter and high gain per unit length. 1.55 micron single frequency high energy and high peak power fiber amplifier is needed for coherent lidar and sensing. In Phase II, we will further optimize the Er ...

    SBIR Phase II 2013 National Aeronautics and Space Administration
  10. Tunable Single Frequency 2.05 Micron Fiber Laser Using New Ho-Doped Fiber

    SBC: AdValue Photonics Inc            Topic: S101

    In this proposal, we propose to demonstrate and build a widely tunable, narrow linewidth, single frequency fiber laser near 2.05 micron by developing an innovative Ho-doped single mode fiber. Such near 2.05 micron fiber laser is needed for coherent lidar and interferometric fiber sensing. Based on our successful demonstration in Phase I, our newly developed Ho-doped fibers have the capability of s ...

    SBIR Phase II 2013 National Aeronautics and Space Administration

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