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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Structural Testing of Branched Timber and Truss Assemblies

    SBC: Whole Trees, LLC            Topic: 81

    USDA secretary, Tom Vilsack, has urged the Forest to prioritize "protecting and maintaining all American Forests, including state and private lands. ... The Forest Service must play a significant role in the development of new markets and ensure their integrity." Small-diameter round timber is a vast and under-used waste product of well-managed forests. At the same time, the structural b ...

    SBIR Phase II 2012 Department of Agriculture
  2. Go Talk Phonics: Phonics for Individuals with Disabilities

    SBC: Attainment Co., Inc.            Topic: N/A

    Purpose: Prior research demonstrates that younger students who are low- or non-verbal often have difficulty independently practicing skills that provide a foundation for early literacy. The proposed product will provide support to students who are low- or non-verbal to independently practice phonics skills associated with early literacy success. Project Activities: The design team will create an ...

    SBIR Phase II 2012 Department of Education
  3. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Point of Care Detection of Respiratory Viruses

    SBC: LUCIGEN CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): Respiratory infections have a significant health and economic impact worldwide. Current test products for the diagnosis of respiratory viral infections such as influenza are inadequate for the timely diagnosis needed for successful implementation of antiviral treatment. Unfortunately a test product that can accurately diagnose common respiratory viruses with hi ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Random Shear Shuttle BAC Libraries for Antimicrobial Discovery from Soil Metageno

    SBC: LUCIGEN CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): 100,000 Americans perish each year due to untreatable bacterial infections. The societal benefits of new antibiotic compounds that are effective against numerous multiple drug resistant pathogens would be significant. The best possible source for new antibiotic structures with potentially novel mechanisms of action is within natural environments, particularly s ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Software to Enrich the Noun Lexicons and Lexical Learning of Children with Autism

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The objective of this project is to develop and field-test prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be 3-8 year old children with Autism Spectrum Disorders (ASD), as well as a broad range of other children with languag ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Engineered tissue-based, high-throughput compound profiling

    SBC: INVIVOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Current NIGMS-SBIR funding supported InvivoSciences LLC's (IVS) launch of several product lines in 2010. IVS generated revenues from the sales of three-dimensional (3D) cell culture tools (MC-8TM and IVS InsertsTM) thatcan grow various hydrogel tissues without any support layers. The culture tools enable Palpator TM and Tissue StretcherTM to stretch the hy ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. NOVEL SOLUBILITY-ENHANCING PROTEIN EXPRESSION TECHNOLOGY

    SBC: LUCIGEN CORPORATION            Topic: NIGMS

    DESCRIPTION (provided by applicant): A major goal in the post-genomic era is to express the vast collection of protein- coding sequences, eventually resulting in a better understanding of protein interactions and the development of novel therapeutics. Themost favored host for heterologous recombinant protein expression is Escherichia coli. Despite many improvements, producing soluble proteins in E ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Intelligent Prosthetic Socket with Variable Volume and Elevated Vacuum Systems

    SBC: SMART SURFACE DESIGNS, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Patient socket performance is a critical barrier to progress in rehabilitation, the most common source of patient dissatisfaction and part of a growing medical and socioeconomic problem. Poor socket performance is a greatly uncharacterized multi-factorial problem that leads to skin degeneration and patient discomfort (~75% of all patients). This proposal has a ...

    SBIR Phase II 2012 Department of Health and Human Services

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