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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Single-Use Delivery Device for Bioabsorbable Fasteners

    SBC: OPUS KSD, INC.            Topic: 100

    DESCRIPTION provided by applicant The surgeonandapos s choice of method for closing incisions is becoming increasingly problematic Metal surgical staples are unacceptable for Minimally Invasive Surgery MIS procedures currently percent of surgeries in the US and are out of favor in traditional procedures due to complications and the cost of staple removal Due to the time required for ma ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Improving Interlock Compliance with Computerized Education and Monitoring Systems

    SBC: AXXESS UNLIMITED, LLC            Topic: 400

    DESCRIPTION provided by applicant All States have enacted laws providing for alcohol ignition interlocks as a sanction for impaired driving Going forward interlock programs may become as widely used with impaired drivers as license suspension even though they are more time consuming and expensive for the government to manage Although the extra expense of managing interlock programs is jus ...

    SBIR Phase II 2015 Department of Health and Human Services
  3. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: EnduRx Pharmaceuticals Inc.            Topic: 102

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM or andquot glioblastoma andquot is the most common and aggressive malignant primary brain tumor in humans An effective treatment that increases patient survival would represent a significant advance in the field and provide a desperately needed new therapy for this deadly disease EnduRx is focused on the development of new tar ...

    SBIR Phase II 2015 Department of Health and Human Services
  4. Developing the Dietary Inflammatory Index for Clinical Application

    SBC: Connecting Health Innovations, LLC            Topic: 300

    DESCRIPTION provided by applicant A large persuasive and ever increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U S including diabetes cardiovascular diseases CVD and cancer Diet plays a central role in the regulation of chronic inflammation However until we developed the dietary infl ...

    SBIR Phase II 2015 Department of Health and Human Services
  5. Mobile multifunctional tool for monitoring and management of respiratory diseases

    SBC: TF HEALTH CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Mobile multifunctional tool for monitoring and management of respiratory diseases Chronic Obstructive Pulmonary Disease COPD and asthma affect millions of people worldwide Because there is no permanent cure for these diseases efficient management of the patients is needed New mobile health technologies such as personal devices that allow patients to monit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Electrochemically Enhanced Plasmonic Imaging for Quantitative Proteomics

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTION provided by applicant We are proposing a technology to help in three key areas of proteomics including a recognition of protein interactions b characterization of post translational modifications and c quantitative measurements at high spatial and or temporal resolution to address the dynamics of protein interactions Several significant types of protein interactions remain ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Closed Loop MAS DNP NMR at K for Affordable Dramatic Gains in S N

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    DESCRIPTION provided by applicant NMR is arguably the most powerful analytical technique for structure determination and function elucidation in molecules of all types but there are complex challenges for biological macromolecules Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS has recently demonstrated S N gains of up to two orders of magnitude at K the lower tempera ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Anatomical Identification at the Microscope using the Brain Navigation System

    SBC: MICROBRIGHTFIELD, INC.            Topic: 101

    DESCRIPTION provided by applicant Microscopic analysis of histologic brain sections yields important information about the organization and composition of the nervous system particularly in modern studies focusing on neuro genomics transcriptomics proteomics and connectomics However identification of distinct brain regions in a section under study with the currently available tools pr ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. FASTCOUNT Next generation stereology platform for fast accurate D cell counting

    SBC: MICROBRIGHTFIELD, INC.            Topic: 101

    DESCRIPTION provided by applicant Stereologic cell counting has revolutionized the field of neuroscience over the last years and numerous studies highlighting the impact of stereologic cell counting in basic neuroscience and pharmaceutical and biotechnology research continue to be published A single study however may take months since investigators must decide by visual inspection whethe ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Neurotensin Fragment for Neuropathic Pain

    SBC: JT Pharmaceuticals, Inc.            Topic: 101

    DESCRIPTION provided by applicant Neuropathic pain management is a major unmet clinical need Classically used medications opioids and non opioids NSAIDs have major side effects associated with their use and many individuals do not respond to any medications Neuropathic pain drugs with novel mechanisms of action are being sought as alternatives however the only novel FDA approved drugs w ...

    SBIR Phase II 2015 Department of Health and Human Services

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