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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme (GBM) is a malignant primary brain tumor affecting about 12,000 new cases per year in the U.S. Average survival is only about 14-15 months. Radiation (RT) is most commonly administered as 30 fractions of 2 Gray each over 6-weeks with concomitant temozolomide (TMZ). GBM tumors are hypoxic. The primary mechanism of RT is creation of singlet oxygen; hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR Phase II: Quasi-Active Prosthetic Ankle System: Dynamic Angle and Stiffness Optimizations for Multiple Gait Activities

    SBC: Springactive, Inc.            Topic: EW

    The broader impact/commercial potential of this project is that the proposed system will enhance the ability of the 1.3 million people currently living in the United States with a lower limb amputation to walk in unconstrained environments. The proposed Quasi-Active Prosthetic Ankle System (QPAS) addresses the RH6: Human Assistive Technologies area. QPAS will be lightweight, have a long battery li ...

    SBIR Phase II 2017 National Science Foundation
  4. Tools for Accelerating R&D for Historically Understudied Protein Kinases

    SBC: LUCEOME BIOTECHNOLOGIES, L.L.C.            Topic: NCATS

    Protein kinases are central players in almost every aspect of human physiology and serve as critical mediators of signal transductionThe dysfunction of many kinases is implicated in cancerdiabetesinflammationand cardiovascular diseases and many are validated targets for therapeutic interventionThe human genome encodesprotein kinasesYettheor so marketed protein kinase drugstarget only a small fract ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Solar-Powered High-Efficiency CO2 Refrigeration Technologies

    SBC: SUNDANZER DEVELOPMENT INCORPORATED            Topic: NonDoD

    SunDanzers High efficiency Refrigeration Unit (HERU) technology is a variable speed, two stage refrigeration platform, initially developed under Army SBIR topic A04-210, and continuing with Army Rapid Innovation Funding. HERU currently uses the military standard hydrofluorocarbon R-134a, vehicle type refrigerant. R-134a leaking into the atmosphere has 1400 times the greenhouse gas effect compared ...

    SBIR Phase II 2017 Department of DefenseArmy
  6. Preclinical development of PPCM vaginal contraceptive to submit IND.

    SBC: YASO THERAPEUTICS INCORPORATED            Topic: NICHD

    PROJECT SUMMARYThe goal of this project is to develop a novel vaginal contraceptive gel product containing PPCM sodium saltPPCMPPCM is a novel polymer drug that inhibits infection of HSVHIVNgonorrhea and is also contraceptiveThis novel drug has an average molecular weight ofis designed to be used topicallyand thus far passed all safety studies and does not appear to be systemically absorbedPPCM ha ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Genotyped and Single Cyst-derived Human ADPKD Cell Platforms for Industry and Academia

    SBC: DISCOVERYBIOMED, INC.            Topic: 100

    DiscoveryBioMedIncDBMIncor DBMspecializes in normal and diseased human cell platform engineeringDBM has assembled a consortium of expertswherebycollectivelywe seek Fast Track SBIR funding to establish and offer a Product Line Menu of normal and ADPKD human cell platforms for the academic and industry marketplacesExisting and interested DBM clients will be presented in terms of which options in the ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Surface Metrology fro X-ray Mirrors using Deflectometry

    SBC: ARIZONA OPTICAL SYSTEMS, LLC            Topic: 04c

    Arizona Optical Systems is developing a measurement technique that enables production of higher accuracy x-ray mirrors for DOE lightsource facilities. Mirror defects, which are too small to measure using existing techniques, degrade beamline performance. Higher accuracy x-ray mirrors increase the energy density of existing sources without requiring new, larger facilities.

    SBIR Phase II 2017 Department of Energy
  9. 21st Century Grid Management- Advanced Big Data Analysis

    SBC: PRIME SOLUTIONS GROUP, INCORPORATED            Topic: 01c

    This project addresses the need for technologies to help electric utility companies evolve toward, and meet the emerging challenges of, the Smart Grid of the future. These tools will help manage and utilize Big Data from the distribution system to facilitate the planning, control, and security of tomorrow’s electric distribution system.

    SBIR Phase II 2017 Department of Energy
  10. Endotoxin Neutralization as a Biomonitor for HIV Disease Progression

    SBC: BIODTECH, INC.            Topic: NIAID

    ABSTRACTEndotoxin neutralization in human plasma is an excellent indicator of chronic immune activationwhich is an accurate predictor of mortality in HIVinfectionRecently we developed an assay using endotoxin neutralization as an indicator of immune activation due to bacterial translocationThis assay is accurate in discriminating healthy patients from those with inflammatory bowel disease in addit ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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