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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microscopic Traffic Simulation Models and Software- An Open Source Approach

    SBC: New Global Systems for Intelligent Transportation Management            Topic: 081FH5

    After successfully developing open source traffic simulation software, ETFOMM (Enhanced Transportation Flow Open-source Microscopic Models), New Global Systems for Intelligent Transportation Management Corp. proposes a US DOT SBIR program to support its efforts to accelerating the commercialization of the software to educational and research communities in Phase IIB. The specific tasks include edu ...

    SBIR Phase II 2015 Department of Transportation
  2. Enhanced baculovirus vectors with higher titers and increased genome stability

    SBC: PARATECHS CORP.            Topic: NIAID

    DESCRIPTION provided by applicant The baculovirus expression vector system BEVS has been successfully utilized to produce thousands of proteins for use as vaccines and therapeutics as well as for studies of protein structure and function One limitation of BEVS is the propensity of baculoviruses to accumulate transposon insertions into the fp k gene leading to the andquot few polyhedra FP ...

    SBIR Phase II 2015 Department of Health and Human Services
  3. A non surgical embryo transfer device for producing gene modified rats

    SBC: PARATECHS CORP.            Topic: 200

    DESCRIPTION provided by applicant ParaTechs Corporation develops innovative technologies for biomedical research while seeking to improve animal welfare for laboratory animals One of ParaTechsandapos major goals is to further the guiding principles of ethical animal use by andapos reducing replacing and refiningandapos the use of animals in research according to the guidelines of Russell a ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Single-Use Delivery Device for Bioabsorbable Fasteners

    SBC: OPUS KSD, INC.            Topic: 100

    DESCRIPTION provided by applicant The surgeonandapos s choice of method for closing incisions is becoming increasingly problematic Metal surgical staples are unacceptable for Minimally Invasive Surgery MIS procedures currently percent of surgeries in the US and are out of favor in traditional procedures due to complications and the cost of staple removal Due to the time required for ma ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Improving Interlock Compliance with Computerized Education and Monitoring Systems

    SBC: AXXESS UNLIMITED, LLC            Topic: 400

    DESCRIPTION provided by applicant All States have enacted laws providing for alcohol ignition interlocks as a sanction for impaired driving Going forward interlock programs may become as widely used with impaired drivers as license suspension even though they are more time consuming and expensive for the government to manage Although the extra expense of managing interlock programs is jus ...

    SBIR Phase II 2015 Department of Health and Human Services
  6. Novel Drug Carrier System for the Treatment of Alcoholic Liver Disease

    SBC: ENDOPROTECH, INC.            Topic: 150

    DESCRIPTION provided by applicant Alcoholic Liver Disease ALD remains a leading cause of death from liver disease in the U S and no FDA approved therapy exists Abnormal cytokine metabolism is a major feature of ALD Elevated serum concentrations of tumor necrosis factor TNF and TNF inducible proinflammatory cytokines chemokines such as IL and IL have been reported in patients w ...

    SBIR Phase II 2015 Department of Health and Human Services
  7. Head-mounted Activity Monitoring(HAM)System Fast Track

    SBC: Gen Nine, Inc.            Topic: NIA

    DESCRIPTION provided by applicant The population of the United States as in most developed nations is aging and is doing so at an increasing rate This change in demographics is having a dramatic effect on the nationandapos s healthcare delivery system and the related public costs The Congressional Budget Office predicts that the cost of long term care for the elderly will reach $ billion ...

    SBIR Phase II 2015 Department of Health and Human Services
  8. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: EnduRx Pharmaceuticals Inc.            Topic: 102

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM or andquot glioblastoma andquot is the most common and aggressive malignant primary brain tumor in humans An effective treatment that increases patient survival would represent a significant advance in the field and provide a desperately needed new therapy for this deadly disease EnduRx is focused on the development of new tar ...

    SBIR Phase II 2015 Department of Health and Human Services
  9. Mobile multifunctional tool for monitoring and management of respiratory diseases

    SBC: TF HEALTH CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Mobile multifunctional tool for monitoring and management of respiratory diseases Chronic Obstructive Pulmonary Disease COPD and asthma affect millions of people worldwide Because there is no permanent cure for these diseases efficient management of the patients is needed New mobile health technologies such as personal devices that allow patients to monit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Electrochemically Enhanced Plasmonic Imaging for Quantitative Proteomics

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTION provided by applicant We are proposing a technology to help in three key areas of proteomics including a recognition of protein interactions b characterization of post translational modifications and c quantitative measurements at high spatial and or temporal resolution to address the dynamics of protein interactions Several significant types of protein interactions remain ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health

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