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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Whole-brain fluorescence and brightfield imaging at single-cell level
SBC: DMetrix, Inc Topic: NIADESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
POPULATION SCALE HLA TYPING FOR HOMELAND DEFENSE
SBC: GENOMICS USA, INC. Topic: N/ADESCRIPTION (provided by applicant): Current technology for HLA typing does not have rapid field response capability because it too expensive and is too complicated to be implemented in the context of a population-scale emergency. The ultimate goal of this proposal is to develop a simple, accurate, low cost method to perform complex HLA typing through development of an "HLA Chip" which will enable ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Optimization, Expansion & Validation of Alzheimers Lymphocyte Proliferation Test
SBC: GW MEDICAL TECHNOLOGIES, LLC Topic: N/ADESCRIPTION (provided by applicant): In GW Medical Technologies' Phase I effort, the company demonstrated the LymProTM (lymphocyte proliferation) Test's feasibility as a blood test for Alzheimer's disease. However, much work still needs to be done to fully prove the LymPro's capabilities and define its limitation before the Test can be useful in a clinical environment. In this proposed effort, GW ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Mass Spectrometry Assays for Biodefense
SBC: INTRINSIC BIOPROBES, INC. Topic: N/ADESCRIPTION (provided by applicant): The objective of this Phase II Research Proposal is to continue the successfully completed work of the Phase I Research project by further developing affinity-based mass spectrometry assays for the detection/characterization of Biodefense agents, specifically the family of Staphylococcal Enterotoxins (SE). The assays will utilize affinity capture in pipette-fit ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Movement Analysis to Monitor Medication Side Effects
SBC: NEUROSCRIPT, LLC Topic: N/ADESCRIPTION (provided by applicant): Clinical trials of new medications often rely on subjective, observer-based ratings of side effects in the form of movement abnormalities to evaluate safety and tolerance of medication dosage. Imprecise ratings of adverse side effects have led to inconsistent results from these trials. Well-known adverse effects are extrapyramidal motor side effects (EPS), whic ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
PI-3 kinase inhibitor PX-866 as anticancer therapy
SBC: PROLX PHARMACEUTICALS CORPORATION Topic: N/ADESCRIPTION (provided by applicant): One in every four deaths in the US is due to cancer. The overall cancer drug market exceeds $2 billion in the USA. There is significant need to identify novel and selective small molecule-based cancer therapies. This proposal seeks to undertake late preclinical development of a novel inhibitor of phosphatidyl inositol 3-kinase for the eventual use of the agent, ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Powers of Inquiry: Using Image Analysis to Explore Environmental Health Science
SBC: SCIENCE-APPROACH Topic: N/ADESCRIPTION (provided by applicant): The goal of this Phase II Small Business Innovative Research (SBIR) application is to create a series of educational materials for the National Institute of Environmental Health Sciences (NIEHS) entitled Powers of Inquiry: Using Image Analysis to Explore Environmental Health Science. The ten lessons to be published by the project will employ four advanced techn ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Thioredoxin Inhibitor, PX-12, in Phase II Clinical Trial
SBC: PROLX PHARMACEUTICALS CORPORATION Topic: N/ADESCRIPTION (provided by applicant): One in every four deaths in the US is due to cancer. The overall cancer drug market exceeds $2 billion in the USA. There is significant need to identify novel, effective, small molecule-based cancer therapies. This proposal seeks to undertake further clinical development of a novel targeted agent, PX-12. ProIX Pharmaceuticals has demonstrated there is strong ev ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
