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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. ABLE Kids II- Advanced Biofidelic Lower Extremity Kids Prosthesis II

    SBC: Orthocare Innovations LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Computerized Orthotic Prescription System- COPS

    SBC: Orthocare Innovations LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Stiffness and alignment of ankle-foot orthoses (AFOs) should be tuned optimally to maximize their function. Improperly tuned AFO may induce joint pain, reduced ambulatory function, and increased medical complications for patients with stroke. Therefore, the relative quality of AFOs fit determined by its stiffness and alignment is of paramount concern in the d ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Development of an Anti-P-selectin Antibody for the Treatment of Sickle Cell Disea

    SBC: SELEXYS PHARMACEUTICALS CORPORATION            Topic: NHLBI

    DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug called SelG1 directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. The ultimate goal of this Phase IIB proposal is to further advance SelG1 into Phase II/III safety and efficacy trials to support of regulatory filings for FDA approval ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Ionomer-membrane Water Processor System Design and EDU Demonstration

    SBC: Paragon Space Development Corporation            Topic: X301

    a. Paragon Space Development Corporation¿ (Paragon) proposes to continue our investigation into the use of microporous-ionomer membrane technology to improve the robustness and effectiveness and simplify water recovery processes for space applications. Improved robustness and effectiveness will be evident through (1) reduced loading onthe downstream post processor due to the ionomer¿s unique pr ...

    SBIR Phase II 2012 National Aeronautics and Space Administration
  6. Frequency-Locked Single-Frequency Fiber Laser at 2 Micron

    SBC: AdValue Photonics Inc            Topic: S101

    Frequency-locked single-frequency 2 micron fiber laser is proposed to be used for airborne/spaceborne coherent lidar measurements, i.e., Active Sensing of CO2 Emissions over Nights, Days, and Seasons. The laser is based on our proprietary fiber technology and extensive experience in fiber laser development, which features a compact, highly stable, frequency-stabilized light source. Advanced freque ...

    SBIR Phase II 2012 National Aeronautics and Space Administration
  7. Multi-Attribute Reliability and Maintainability Engineering Assessment Methodology

    SBC: ANAUTICS, INC.            Topic: AF093193

    ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning data: more data is being manufactured by machines, servers, mobile devices, and software applications ...

    SBIR Phase II 2012 Department of DefenseAir Force
  8. Non-Intrusive Direct Part Marking with Femtosecond Laser Pulses

    SBC: Physics, Materials, and Applied Mathematics Research L.L.C.            Topic: AF093191

    ABSTRACT: In Phase I, we presented options for direct marking of high-performance turbine parts using ultrashort pulse lasers, that do not compromise the integrity of said parts. In the proposed effort, we will work with our customer to: evaluate metallurgy and fatigue, and mark quality on the range of materials used for fracture critical parts; develop marking conditions for all major alloys to ...

    SBIR Phase II 2012 Department of DefenseAir Force
  9. Terahertz Station Keeping Equipment for Tunable Range Capabilities

    SBC: Physics, Materials, and Applied Mathematics Research L.L.C.            Topic: AF103002

    ABSTRACT: Current station keeping equipment (SKE) relies on radio waves for formation flying. A significant limitation of conventional SKE signals is that they are detectable at long distances by adversaries. Passive detection schemes that employ infrared and thermal cameras, electro-optic and acoustic sensors are of interest for future SKE upgrades although they lack the capability to provide su ...

    SBIR Phase II 2012 Department of DefenseAir Force
  10. Expert Troubleshooting and Repair System

    SBC: RIDGETOP GROUP, INC.            Topic: AF093208

    ABSTRACT: Ridgetop Group, Inc. will design and develop a prototype of an electronic warfare (EW)"Expert Troubleshooting and Repair System"that has the following characteristics: (1) troubleshooting support that presents a prioritized list of methods; (2) a list of test-dependent action(s), including recommended repair actions; and (3) an Analog-Degradation Detection and Analysis (ADDA) tester. Tr ...

    SBIR Phase II 2012 Department of DefenseAir Force

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