Award Data

a. Paragon Space Development Corporation¿ (Paragon) proposes to continue our investigation into the use of microporous-ionomer membrane technology to improve the robustness and effectiveness and simplify water recovery processes for space applications. Improved robustness and effectiveness will be evident through (1) reduced loading onthe downstream post processor due to the ionomer¿s unique pr ...

Future NASA Space Science Missions will incorporate detectors, sensors, shields, and telescopes that must be cooled to cryogenic temperatures. An enabling technology for these missions is advanced cryocoolers that can provide continuous and distributed cooling with minimal input power. On this program, Creare proposes to develop and demonstrate an innovative cryocooler that produces refrigeratio ...

This proposal is responsive to NASA SBIR Topic X10.01, specifically, the need for efficient small- to medium-scale hydrogen liquefaction technologies, including domestically produced wet cryogenic turboexpanders. Future NASA missions will require hydrogen liquefaction systems for spaceport, planetary, and lunar surface operations. A critical part of these systems is the cryogenic expansion turbi ...

Frequency-locked single-frequency 2 micron fiber laser is proposed to be used for airborne/spaceborne coherent lidar measurements, i.e., Active Sensing of CO2 Emissions over Nights, Days, and Seasons. The laser is based on our proprietary fiber technology and extensive experience in fiber laser development, which features a compact, highly stable, frequency-stabilized light source. Advanced freque ...

DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

DESCRIPTION (provided by applicant): There is currently no effective treatment for recurrent small-cell lung cancer (rSCLC). The objective of this project is to utilize a monoclonal antibody, Abner, to develop new, rational, and successful treatment of rSCLC. The hypothesis being tested is that an abnormal vasopressin type 2 receptor (AbnV2R) present on these tumors will provide a sensitive, tumor ...

DESCRIPTION (provided by applicant): Anterior cruciate ligament (ACL) injuries are a significant problem for athletes, and women in particular. Both surgical and non-surgical treatment options exist, with the ultimate goal of regaining joint stability, knee kinematics, and quadriceps strength compared to the uninjured contralateral limb to allow full return of function and activity level and to p ...

DESCRIPTION (provided by applicant): MI is the leading cause of death in the developed world, including the United States. In 2005 over 8.1 million Americans had an MI; 30% died before reaching hospital and 10% died after hospitalization. It is the 70% whoreach hospital that we believe we can help - a million lives in the balance and an improved quality of life for millions more - in the US alone. ...

DESCRIPTION (provided by applicant): The global burden of cancer doubled between 1975 and 2000. Cancer became the leading cause of death worldwide in 2010, and is projected to double again by 2020 and to triple by 2030. This horrible disease has touched each of us, and despite enormous investments in prevention and treatment, its impact continues to accelerate. Ideally, any cancer therapy should ...

There is an urgent need to develop a new high-energy 2m ultrafast fiber laser system in order to achieve the optimized efficiency of the ESASE process, which is beneficial in areas ranging from atomic and molecular sciences to chemical, materials, and biological studies. To reach the mid-IR wavelengths for ESASE application, the traditional way is to shift the wavelengths of these commercially ava ...