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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improving Interlock Compliance with Computerized Education and Monitoring Systems

    SBC: AXXESS UNLIMITED, LLC            Topic: 400

    DESCRIPTION provided by applicant All States have enacted laws providing for alcohol ignition interlocks as a sanction for impaired driving Going forward interlock programs may become as widely used with impaired drivers as license suspension even though they are more time consuming and expensive for the government to manage Although the extra expense of managing interlock programs is jus ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A Wheelchair Anti-Rollback Device

    SBC: GREEN TECHNOLOGIES, INC.            Topic: NIA

    DESCRIPTION provided by applicant Wheelchairs in the modern form have been around since at least when John Joseph Merlin invented pushrim propulsion The Merlin Chair as it was called bears a remarkable resemblance to wheelchairs today despite the intervening years The conventional pushrim operated wheelchair has become the prevalent assistive care mobility device because of its ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: ENDURX PHARMACEUTICALS INC            Topic: 102

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM or andquot glioblastoma andquot is the most common and aggressive malignant primary brain tumor in humans An effective treatment that increases patient survival would represent a significant advance in the field and provide a desperately needed new therapy for this deadly disease EnduRx is focused on the development of new tar ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Mobile multifunctional tool for monitoring and management of respiratory diseases

    SBC: TF HEALTH CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Mobile multifunctional tool for monitoring and management of respiratory diseases Chronic Obstructive Pulmonary Disease COPD and asthma affect millions of people worldwide Because there is no permanent cure for these diseases efficient management of the patients is needed New mobile health technologies such as personal devices that allow patients to monit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Electrochemically Enhanced Plasmonic Imaging for Quantitative Proteomics

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTION provided by applicant We are proposing a technology to help in three key areas of proteomics including a recognition of protein interactions b characterization of post translational modifications and c quantitative measurements at high spatial and or temporal resolution to address the dynamics of protein interactions Several significant types of protein interactions remain ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Enzyme replacement therapy for Sanfilippo A lysosomal rare disease

    SBC: BIOSTRATAGIES LC            Topic: 107

    DESCRIPTION provided by applicant The goal of this SBIR proposal is to develop an effective enzyme replacement therapy ERT for Sanfilippo A patients by exploiting safety supply and cost advantages of plant based enzyme bioproduction while integrating novel ERT delivery strategies being development at BioStrategies LC Sanfilippo A MPS IIIA is a rare genetic lysosomal storage disorder affe ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. PlayTalk Communication Software for Children with Complex Communication Needs

    SBC: INVOTEK, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): There is an urgent need for speech generating devices (SGDs) designed for young children with complex communication needs. Available SGDs are difficult for children to use and time consuming for adults to program. Without appropriate SGDs, children miss valuable opportunities to communicate and develop language skills during their early years, when they are pr ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. OTHER FUNCTIONS TARGET SPECIFIC AND DRUG LOADED IRON OXIDE NANOPARTICLES FOR CANCER IMAGING AND THERAPY.

    SBC: Ocean Nanotech LLC            Topic: NCI

    Breast cancer is the most common type of cancer and the second leading cause of cancer death among women with more than one million new cases and 370,000 deaths worldwide yearly. Chemotherapy drugs, such as Doxorubicin, have been used in both pre- and post-operative adjuvant therapy or as the main therapeutic option for breast cancer patients with metastatic disease. Although recent advances in th ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. IGF::OT::IGF OTHER FUNCTIONS RandD- MEDICAL: BIOMEDICAL (BASIC RESEARCH), MULTI-BIOMARKER IMAGING USING QUANTUM DOTS FOR PREDICTION OF HPV-ASSOCIATED CANCER

    SBC: Ocean Nanotech LLC            Topic: NCI

    The goal of this project is to develop multiple-biomarker imaging for detection of human papillomavirus (HPV) associated human cancer. Quantum dots (QDs) with multiple emission colors were chosen as optical probes to label the biomarkers on tissue. Attribute to the unique optical properties of QDs, they can be used as powerful cancer diagnostic tools providing the molecular profiles of cancer ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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