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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. DEVELOPMENT OF PALYTOXIN IMMUNOTOXINS PHASE I

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO ESTABLISH METHODS FOR CONJUGATING THE POTENT MARINE TOXIN, PALYTOXIN TO ANTIBODIES IN SUCH A WAY THAT SPECIFIC CYTOTOXICITY OF TARGET CELLS IS POSSIBLE. THE PRODUCT, IMMUNOPALYTOXIN (IPT), SHOULD BE EASILY PREPARED, HAVE HIGH SPECIFIC CYTOTOXIC ACTIVITY AND BE MINIMALLY TOXIC TO UNRELATED CELLSOR INTACT ANIMALS. THIS WORK WILL INVESTIGATE CHEMICAL LINKAGES BETWE ...

    SBIR Phase II 1984 Department of Health and Human Services
  2. RAPID DETECTION OF CARBOFURAN IN FOOD AND ENVIRONMENTAL SAMPLES.

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    WE PROPOSE TO DEVELOP AN IMMUNOASSAY FOR THE PESTICIDE, CARBOFURAN. PHASE I WILL CONSIST OF SYNTHESIZING SUITABLE HAPTENS, CONJUGATING THESE HAPTENS TO AN IMMUNOGENIC CARRIER, PREPARING AND SCREENING RABBIT ANTISERA, AND CONDUCTING PRELIMINARY COMPETITIVE ELISA TESTS TO DEMONSTRATE THE FEASIBILITY OF THIS APPROACH TO A RAPID, ECONOMICAL PESTICIDE DETECTION SYSTEM.

    SBIR Phase II 1985 Department of Agriculture
  3. UTILIZATION OF INNOVATION AQUACULTURE TECHNIQUES IN THE PRODUCTION OF SUPERIOR QUALITY NORI

    SBC: Aquaculture Concepts            Topic: N/A

    THE GOAL OF THIS R&D PROJECT IS TO DETERMINE IF SUPERIOR QUALITY NORI CAN BE RAISED ON A COMMERCIAL SCALE UTILIZING INNOVATIVE AQUACULTURE METHODS. THREE MAJOR EXPERIMENTS WILLTEST THE NEW TECHNIQUES DESIGNED FOR A COMMERCIAL FARM. THE OBJECTIVES ARE 1) DETERMINE THE EFFECTIVENESS OF THE GROWOUTTANK; 2) TEST THE NURSERY TANK AND DESIGN AND DEVELOP ASSOC IATED METHODOLOGIES; 3) DETERMINE THE ACTUAL ...

    SBIR Phase II 1987 Department of Agriculture
  4. IMAGING IR SPECTROMETER

    SBC: Sets Technology Inc            Topic: N/A

    THIS PROPOSAL RESPONDS TO TECHNICAL SUBTOPIC 08.27: MULTI-CHANNEL INFRARED SPECTROMETER, WHICH REQUESTED A SPECTROMETER BE DEVELOPED CAPABLE OF SAMPLING SIMULTANEOUSLYTHE SPECTRAL RANGE 1.0 TO 2.5 AT 1% RESOLUTION WITH A NEP OF 10-16 W/HZ. THE OPPORTUNITY IS TO APPLY NEW IR ARRAY DETECTORS AND OPTICAL DESIGNS TO MEET AND EXCEED THESE SPECIFICATIONS, AND PERHAPS TO DEVELOP A TRULY IMAGINGSPECTROMET ...

    SBIR Phase II 1988 National Aeronautics and Space Administration
  5. DENGUE VACCINE DEVELOPMENT

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    THE ULTIMATE OBJECTIVE OF THIS PROJECT IS THE PRODUCTION OF A DENGUE VACCINE. THE FOUR DENGUE VIRUSES (SEROTYPES) AS A GROUP ARE BY FAR THE MOST IMPORTANT VIRUSES TRANSMITTED TO MAN BY ARTHROPODS AND IN TERMS OF GLOBAL MORBIDITY ARE RESPONSIBLE FOR SEVERAL HUNDRED THOUSAND TO SEVERAL MILLION CASES ANNUALLY. IN PHASE I RANDOM FRAGMENTS OF THE DENGUE VIRUS 2 (RNA) GENOME WILL BE CLONED INTO A BACTER ...

    SBIR Phase II 1988 Department of DefenseArmy
  6. TETRODOTOXIN IMMUNOASSAYS

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    TETRODOTOXIN IS A HIGHLY POTENT LOW MOLECULAR WEIGHT NEUROTOXIN FOUND IN SOME SPECIES OF PUFFERFISH AND A FEW OTHER WIDELY DIVERGENT ORGANISMS. CURRENTLY, TETRODOTOXIN IS MEASURED BY MOUSE BIOASSAY OR WITH SOPHISTICATED CHROMATOGRAPHIC METHODS. A SIMPLE, SPECIFIC, EASY TO USE ASSAY METHOD FOR TETRODOTOXIN IS NEEDED. IMMUNOASSAYS ARE USED FOR DETERMINATION OF BIOLOGICALLY IMPORTANT SMALL MOLECULES ...

    SBIR Phase II 1988 Department of DefenseArmy
  7. ULTRASONIC SPATIAL SENSING AID FOR THE BLIND

    SBC: Multipath Systems, Inc            Topic: N/A

    THE PROPOSED ULTRASONIC SPATIAL SENSING AID FOR THE BLIND IS AN ELECTRONIC TRAVEL AID DESIGNED TO PROVIDE THE BLIND TRAVELER WITH SPATIAL CONTEXTUAL INFORMATION, A NECESSARY PREREQUISITE FOR MOBILITY. THE DEVICE OPERATES ON THE ECHOLOCATING PRINCIPLE, BY BROADCASTING ULTRASOUND WHICH IS REFLECTED BY ENVIRONMENTAL OBJECTS. THE RETURNING ULTRASONIC ECHOES WILL BE ELECTROACOUSTICALLY TRANSFORMED INTO ...

    SBIR Phase II 1989 Department of Health and Human Services
  8. HYPERSPECTRAL IMAGE EXPLOITATION

    SBC: Sets Technology Inc            Topic: N/A

    THIS PROPOSAL RESPONDS TO DOD TECHNICAL SUBTOPIC A88-162: HYPERSPECTRAL/IMAGE EXPLOITATION, WHICH REQUEST THE DESIGN AND IMPLEMENTATION OF SOFTWARE FOR HYPERSPECTRAL IMAGE EXPLOITATION. THE RESULT WOULD BE THE DEVELOPMENT OF A INTEGRATED SYSTEM WHICH WOULD ALLOW THE ARMY TO EVALUATE THE POTENTIAL APPLICATIONS FOR APPLYING HYPERSPECTRAL IMAGING SPECTROSCOPY FOR THE DETECTION AND IDENTIFICATION OF M ...

    SBIR Phase II 1989 Department of DefenseArmy
  9. DEVELOPMENT OF AN ECONOMICALLY COMPETITIVE OYSTER/SHRIMP PRODUCTION SYSTEM

    SBC: Aquaculture Technology            Topic: N/A

    THE RESEARCH WILL PROVIDE TECHNICAL INFORMATION ON THE PRODUCTION OF PREMIUM QUALITY HALF-SHELL OYSTERS USING SHRIMP POND EFFLUENT. SHRIMP POND WATER IS PUMPED THROUGH FLUIDIZED OYSTER COLUMNS, PASSED THOUGH SEDIMENTATION TANKS,AND RETURNED TO THE POND. WHEN FED TO OYSTERS, THE ALGAE- LADEN POND WATER CAN PRODUCE MARKET-SIZE OYSTERS IN LESS THAN 200 DAYS. IN THE FLUIDIZED COLUMNS, THE OYSTERS ARE ...

    SBIR Phase II 1991 Department of Agriculture
  10. PRODUCTION OF DENQUE 2 ENVELOP PROTEIN IN THE YEAST SACCHAROMYCES CEREVISIAE

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    THE FOUR SEROTYPES OF DENGUE VIRUSES ARE A LEADING CAUSE OF MORBIDITY THROUGHOUT THE TROPICS AND SUBTROPICS. FOR USE IN DIAGNOSTICS AND IN SUBUNIT VACCINES AGAINST DENGUE, A RELIABLE AND INEXPENSIVE SOURCE OF DENGUE ANTIGENS IS REQUIRED. FOR THESE PURPOSES, EXPRESSION OF RECOMBINANT ANTIGENS IN MICROORGANISMS IS BEST SUITED. WE PROPOSE TO USE THE YEAST SACCHAROMYCES CEREVISIAE TO PRODUCE THE DENGU ...

    SBIR Phase II 1991 Department of DefenseArmy

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