Award Data

ABSTRACT / PROJECT SUMMARY Stroke affects more than 795,000 patients per year in the US and kills approximately 40,000. Long-term medical care expense for stroke in the US, costs over $34B per year. Large vessel occlusion (LVO) stroke accounts for almost 40% of ischemic strokes but causes 95% of mortality and 62% of long-term dependence. Mechanical thrombectomy (MT), or a combination of MT and tPA ...

Project Summary Toxoplasma gondii (T.gondii), the causative agent for toxoplasmosis, invades host cells through ingestion of uncooked infected meat or contaminated water. T.gondii infects 30% of the world’s population and the current cost of the disease in US itself is estimated to be $3B and rising. Current treatment regimen is effective only against acute infection and has severe side effects. ...

PROJECT SUMMARY This proposal is submitted in direct response to NOT-HD-22-009 Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities [IDD] (R43/R44). Persons of all ages with certain metabolic disorders are at-risk for metabolic crises when a certain metabolite accumulates, whi ...

Breault Research is proud to provide our Navy customer with the technology and tools to design, produce and field a true Twenty First Century warhead. Breault’s Adaptive Multi-Mission Ordnance (AMMO) incorporates state-of-the-art lethality materials and flexible configurations to optimize warhead effectiveness in a smaller form factor. Breault’s unique design and production processes provide t ...

As a response to the Navy SBIR Topic N212-126, GHz Optical Underwater Detection Receiver, Alphacore will develop a wide bandwidth, multi-element optical receiver to enable the extraction of both reflectivity and range features of objects in water. This proposed work will integrate advanced compact photo detectors with Alphacore’s innovative high-speed readout technology. The proposed system will ...

This Phase II program addresses the need for more reliable thermal protection systems (TPS) for hypersonic aerial vehicles operating in hypersonic flight environments.    A novel manufacturing process is proposed that allows for controlled porosity structures including layer-to-layer variations that can be tailored for the particular application and material property needs.   In this program, ...

NP Photonics proposes to develop a compact high-power mid-wave infrared laser system by taking advantage of its substantial capability and experience in mid-wave infrared fibers and fiber lasers. The proposed mid-wave infrared laser system has the advantages of high-efficiency, high power scalability, high beam quality, and broad spectral coverage. In the Phase I program, the feasibility of deve ...

In this Phase I project, Oceanit will design a self-healing computing system for use on Navy vessels to keep a ship's primary functions operational in combat should the original computing system be damaged during an attack.

Hydronalix will develop and demonstrate agile, rapid, on-demand domestic manufacturing of low-cost self-propelled rescue can. Based on the advanced domestic manufacturing capabilities developed in a related Phase I and Phase II program for Unmanned Air Vehicles (UAS) this program proposes to develop a new low cost self-propelled rescue can.  Current rescue cans are incapable of propelling themsel ...

Current treatments for asthma, while reducing exacerbations in a subset of patients by focusing on airway inflammation, do not eliminate them. Asthma exacerbations are a significant cause of morbidity and mortality in asthma as they can lead to airway injury, lung function decline and death. Exacerbations in more severe asthmatics are of particular concern, as health care costs and lost productivi ...