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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD10102

    To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to advance development of a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses mature components ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. 3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD10103

    Poor drug candidates are often identified late in the drug development process (e.g., in the preclinical and clinical phases) and contribute significantly to the high cost and low yield of drug discovery. As a result, new tools are needed to accelerate the assessment of drug candidate toxicity earlier in the drug development process. To address this Chemical/Bio Defense (CBD) need, Physical Optics ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. Next Generation Integrated Electrophoretic Nanofluidic Biochip Sensor Platform for the THz Spectroscopic Finger Printing of Biological Species and Age

    SBC: Redondo Optics, Inc.            Topic: CBD10110

    Redondo Optics Inc. (ROI), proposes to develop and demonstrate a next generation integrated electrophoretic nanofluidic biochip (INTRay-Nanochip) sensor platform for the"label-less"THz spectroscopy finger printing of biological species and agents. In the proposed Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. Miniature Residual Life Indicator

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD10106

    To address the Chemical and Biological Defense (CBD) need for a residual life indicator (RLI) capable of determining the degradation in physical adsorption and reactive capacity arising from battlefield contaminants and exposure to the elements, Physical Optics Corporation (POC) proposes to continue the development of a new Miniature Residual Life Indicator (MRLIN). MRLIN is based on impedance spe ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Predicting Ultra High-Performance Concrete (UHPC) Residual Strength after Multiple Penetrations and Blasts

    SBC: Karagozian & Case            Topic: DTRA092013

    The primary objective for the proposed effort is to develop innovative fast-running models (FRMs) that are based on data generated by High-Fidelity Physics-Based (HFPB) models; these FRMs are to predict the damage, responses, and subsequent residual strength of walls and slabs composed of UHPC or HPC materials of the kind that would be used in hardened bunkers. Of particular interest is to create ...

    SBIR Phase II 2011 Department of DefenseDefense Threat Reduction Agency

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