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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States

    SBC: NEW MEXICO START-UP FACTORY II LLC            Topic: NIGMS

    Project Summary As a participant in the new IDeA Regional Entrepreneurship Development (I-RED) program, the goal of this proposal is to create an educational product to promote entrepreneurism and commercialization in the Mountain West region of IDeA states. The educational product and overall program are intended to address the needs of IDeA state academic institutions in developing and strengthe ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. HEALS™: An Active Hydrogen Sulfide Delivery Technique for Accelerated, Effective Wound Healing

    SBC: EXHALIX LLC            Topic: 300

    Project Summary/Abstract The proposed effort addresses the need for novel therapeutic tools that improve chronic wound healing outcome. Recent studies show that patients with diabetic foot ulcers have a 40% recurrence rate within 1 year after treatment and healing, nearly 60% within 3 years, and 65% within 5 years, while the 5-year mortality rate is exceeded only by lung cancer. Lower limb wounds ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Aerosolized Epigenetic Therapy for Metastatic Lung Cancer

    SBC: Nob Hill Therapeutics, Inc.            Topic: 102

    Project SummaryLung cancer (LC) with over 2 million cases/year worldwide also remains the leading cause of cancer- related death in the US and Europe. Treating LC remains challenging due to ~60% of patients presenting with Stage IV disease, the heterogeneity of tumors with respect to genetic and epigenetic mechanisms that alter gene expression, and treatment-related resistance. Combining chemother ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. A Broadband and Compact Dual Comb Spectrometer for Precise Field Detection of Trace Elements and Chemicals

    SBC: OPTICSLAH, LLC            Topic: DTRA20B003

    There is a growing need to accurately characterize nuclear materials not only for nuclear safeguards and nonproliferation treaty verification but also for forensics and provenance. At present, nuclear material identification requires samples to be collected and sent to laboratories for analysis using large and expensive equipment, such as inductively coupled plasma mass spectrometers (ICP-MS) or s ...

    STTR Phase II 2023 Department of DefenseDefense Threat Reduction Agency
  5. Efficient Machine Learning Algorithms for Information Fusion from Radiation Detectors

    SBC: XL SCIENTIFIC LLC            Topic: DTRA212006

    This proposal for Phase II in response to the Defense Threat Reduction Agency (DTRA) topic 212-006 “Algorithm that can locally link radiation detectors (of different resolutions) to enhance identification/ localization capability”. The topic describes the need for an algorithm to support the fusion of multiple and varied detector outputs into actionable information. The specific focus is to id ...

    SBIR Phase II 2023 Department of DefenseDefense Threat Reduction Agency
  6. Cloud-based Automated Electronic Monitoring for Fisheries of the Future

    SBC: AIFISH LLC            Topic: 93

    Electronic monitoring (EM) represents a promising opportunity for fishery management of the future. Yet after nearly two decades of implementation less than 1% of the world’s fishing fleet are able to participate in these programs. Cost remains a key barrier to the implementation of these programs and the primary cost drivers are manual video review, data transmission and data storage. Our SBIR ...

    SBIR Phase II 2023 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Algorithm to Identify Patients at Risk of Medication-Related Hospitalization

    SBC: L. KRENK, INC.            Topic: R

    The long-range goal of this fast-track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication-related hospitalization. The specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication-related hospitalization so t ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. RECOMBINANT WEST NILE VIRUS VACCINE ADJUVANTED WITH SLA-LSQ

    SBC: HAWAII BIOTECH, INC.            Topic: 105

    The contract supports the development of TLR4 agonist within an oil-in-water emulsion as a vaccine adjuvant. The adjuvant development activities are being conducted within the context of vaccines to protect against West Nile virus infection.

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Single molecule DNA/RNA sequencing technology based on a parallel Raman scattering readout in a coupled nanochannel/nanopore system

    SBC: ARMONICA TECHNOLOGIES, INC.            Topic: 172

    Single molecule DNA/RNA transport and Raman sequencing technology based on parallel Ramanscattering readout in a coupled nanochannel/nanopore system. Abstract Armonica Technologies, Inc. is proposing to develop a novel, high-throughput, label-free, highly accurate, long-read DNA sequencing platform based on inexpensive nanoscale patterning and self- assembly. The platform consists of nanochannels ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Development of NH101: A Simple and Efficient Outpatient Dry Powder Amphotericin B-DryNeb(dry powder nebulizer) for Treatment of Susceptible and Multidrug Resistant Aspergillus/ Fungal Infections

    SBC: Nob Hill Therapeutics, Inc.            Topic: NHLBI

    Project Summary The overall objective of this project is to build on the successes of our Phase I SBIR studies to progress NH101: a pure (neat) dry powder of amphotericin B (AMB) combined with the DryNeb™, a novel dry powder nebulizer to “clinic ready” status. The results of this program will enable a Phase I clinical study (AUS), engagement with the FDA on the NH101 505(b)(2) regulatory app ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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