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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Topic 345: RadTox- Measuring Radiation Toxicity using Circulating DNA

    SBC: DiaCarta, Inc.            Topic: NCI

    The QuantiDNA RadTox System is a unique, patented technology that measures tissue damage shortly following injury using cell-free DNA from a drop of blood. Premised on murine and primate studies showing circulating DNA is logarithmically increased with whole-body radiation dose, RadTox has the potential to overcome many of the species-specific challenges faced by biomarker panels. The phase I SBIR ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 349: Quantum Dot FRET Immunoassay to Quantify Intramolecular Epitopes of Analytes in Tissue Sections

    SBC: Ocean Nano Tech LLC            Topic: NCI

    This proposal is to develop a novel slide based proximity assay platform to quantify protein phosphorylation on tissues. The novelty of this assay platform is derived from the use of the quantum dot with two emission peaks for fluorescence resonance energy transfer (FRET): one emission as internal standard and the other as FRET donor. Change of ratio of the two emission intensity during the FRET c ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Tissue Oxygen Monitoring in Peripheral Vascular Disease

    SBC: PROFUSA, INC.            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe goal of this Fast Track SBIR is to demonstrate the functionality of PROFUSAandapos s novel injectable tissue oxygen monitors in patients with peripheral arterial diseasePADand to determine the its ability to detect restenosis in critical limb ischemiaCLIPAD is a manifestation of systemic atherosclerosis that affectsmillion people in the U Swith prevalence increa ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Smokescreen Translational (TL) Analysis Platform

    SBC: BioRealm LLC            Topic: 500

    Project Summary Tobacco attributable disease remains the largest potentially modi able cause of mortalityStrategies to reduce smoking prevalence include developing more effective smoking cessation treatmentsNicotine metabolism and dependence are predictors of smoking behaviorsincluding response to smoking cessation treatmentsThe goal of this Phase II project is to develop prediction models of nico ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Use of DNATrax and high fidelity computational methods to model transport of contaminants in urban environments

    SBC: Safetraces, Inc.            Topic: NIEHS

    PROJECT SUMMARY ! The abundance of airborne micron sized pollutant correlates with the prevalence and severity of respiratory diseaseswhich represents therd leading cause of death in the United States and have an economical cost of tens of billions of dollars per yearGrowing concerns on the possibility of terrorist attacks have motivated efforts in preparing for and responding to airborne releases ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. V-Motive: System for Comprehensive Therapy-Integrated Video Modeling

    SBC: EXPERIAD LLC            Topic: 104

    DESCRIPTIONprovided by applicantThis fast track SBIR will result in a new type of software systemcalled V Motivewhich will facilitate the combination of two proven autism behavioral interventionsApplied Behavior Analysis therapyABAand Video ModelingVMV Motive will have the potential to change how ABA therapy is performed by making it feasible for therapy providers to leverage VM in a comprehensive ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Accelerating Multi-modal Biomarker Discovery in Translational Research with Cloud Data Integration

    SBC: CYTOBANK, INC.            Topic: 400

    Project Summary Abstract Cytobank is the leading cloud based platform for analysis and storage of single cell flow and mass cytometry datatechnologies that are essential for investigating the interplay between the immune system and disease conditions including cancerThere are numerous data analysis steps between raw data and insight especially for many single cell technologieswhere the data analys ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Wireless Sensor Inserts for Combating Incontinence-Associated Dermatitis

    SBC: JPTECHNOLOGIES, INC.            Topic: 600

    Incontinence affects almost two thirds of nursing home residents and half of acute care patientsHalf of these incontinence patients and a third of diapered children suffer from incontinence associated dermatitisIADa skin inflammation resulting from exposure to urine and or feces as a result of incontinenceIAD increases the risk of developing microbial skin infections and pressure ulcersDelays in c ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Comprehensive but simple encoding of bioassays to accelerate translational drug discovery

    SBC: COLLABORATIVE DRUG DISCOVERY, INC.            Topic: 100

    PROJECT SUMMARY Collaborative Drug DiscoveryIncCDDproposes to extend its innovative software platformBioAssay ExpressBAEversionwhich helps biologists to quickly and easily encode their plain text biological assay protocols into formats suitable for computational processingIn PhaseBCDD will further enhance BAE so that it can markup a bioassay with a comprehensivedetailed set of annotations that com ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. Aerosol Delivery of Surfactant for ARDS

    SBC: KAER BIOTHERAPEUTICS CORPORATION            Topic: NHLBI

    Acute respiratory distress syndromeARDSafflicts aboutAmericans each yearThe pathology consists of rapid onset of respiratory symptoms including radiographic bilateral opacities and pulmonary edemaThe primary risk factors for the development of ARDS are pneumoniaaspirationmajor traumasepsisand inhalation injuryDespite the adoption of lung protective ventilationthe mortality rate remains aboutCommon ...

    SBIR Phase II 2018 Department of Health and Human Services

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